SCHEMBL3534451

SCHEMBL3534451

Cn1ccnc1-c1ncc[nH]1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 2/20 0.46
NISCH Q9Y2I1 2/20 0.46
ALDH1A1 P00352 3/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MTOR P42345 1/20 0.39
ADK P55263 1/20 0.39
LPO P22079 1/20 0.39
KDM4E B2RXH2 3/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
HSD17B10 Q99714 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
SMPD3 Q9NY59 1/20 0.35
NPC1 O15118 1/20 0.35
PKM P14618 1/20 0.35
RAB9A P51151 1/20 0.35
PDE10A Q9Y233 1/20 0.34
CYP1A2 P05177 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12075550 0.79 KDM4E (0.40) BRD4NISCHALDH1A1MTORADK
SCHEMBL308400 0.75 LPO (0.55) BRD4ALDH1A1LPOKDM4ECASP1
SCHEMBL11120819 0.73 KDM4E (0.40) BRD4LPOKDM4ECASP1CASP7
SCHEMBL31153305 0.73 LPO (0.52) BRD4ALDH1A1LPOKDM4ECASP1
Hydrochloric Acid SCHEMBL1806963 0.73 LPO (0.52) BRD4ALDH1A1LPOKDM4ECASP1
SCHEMBL17517258 0.73 KDM4E (0.43) BRD4ALDH1A1KDM4ECASP1CASP7
SCHEMBL5476182 0.72 LMNA (0.41) BRD4NISCHALDH1A1SMN1; SMN2MTOR
SCHEMBL11011484 0.71 NISCH (0.38) BRD4NISCHALDH1A1SMN1; SMN2MTOR
SCHEMBL6017638 0.71 NISCH (0.38) BRD4NISCHALDH1A1MTORADK
SCHEMBL11503499 0.71 ALDH1A1 (0.61) BRD4NISCHALDH1A1SMN1; SMN2MTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0086102-B1 POYOL/IMIDAZOLE CURING AGENTS FOR EPOXY RESINS INTEREZ, Inc.(a Delaware corporation) (US) 1986-06-04 EP claimed
US-12157785-B2 Poly(allyl glycidyl ether)-based redox polymer and electrochemical biosensor using same I-SENS, INC. (KR) 2024-12-03 US disclosed
EP-3854827-B1 OXIDATION-REDUCTION POLYMER INCLUDING TRANSITION METAL COMPLEX, AND ELECTROCHEMICAL BIOSENSOR USING SAME I SENS INC (KR) 2023-11-08 EP disclosed
EP-3854827-B1 OXIDATION-REDUCTION POLYMER INCLUDING TRANSITION METAL COMPLEX, AND ELECTROCHEMICAL BIOSENSOR USING SAME I SENS INC (KR) 2023-11-08 EP disclosed
EP-4010398-A1 ADHESIVE COMPOSITIONS PPG Industries Ohio Inc. (US) 2022-06-15 EP disclosed
US-20220025114-A1 POLY(ALLYL GLYCIDYL ETHER)-BASED REDOX POLYMER AND ELECTROCHEMICAL BIOSENSOR USING SAME I-SENS, INC. (KR) 2022-01-27 US disclosed
US-20220025114-A1 POLY(ALLYL GLYCIDYL ETHER)-BASED REDOX POLYMER AND ELECTROCHEMICAL BIOSENSOR USING SAME I-SENS, INC. (KR) 2022-01-27 US disclosed
US-20210347926-A1 OXIDATION-REDUCTION POLYMER INCLUDING TRANSITION METAL COMPLEX, AND ELECTROCHEMICAL BIOSENSOR USING SAME I-SENS, INC. (KR) 2021-11-11 US disclosed
US-20210347926-A1 OXIDATION-REDUCTION POLYMER INCLUDING TRANSITION METAL COMPLEX, AND ELECTROCHEMICAL BIOSENSOR USING SAME I-SENS, INC. (KR) 2021-11-11 US disclosed
EP-3854833-A1 POLY(ALLYL GLYCIDYL ETHER)-BASED REDOX POLYMER AND ELECTROCHEMICAL BIOSENSOR USING SAME i-Sens, Inc. (KR) 2021-07-28 EP disclosed
US-20080248354-A1 Enzyme Electrode, and Device, Sensor, Fuel Cell and Electrochemical Reactor Employing the Enzyme Electrode CANON KABUSHIKI KAISHA (JP) 2008-10-09 US disclosed
EP-1807407-A1 AROMATIC AMIDES AS INHIBITORS OF C-FMS KINASE JANSSEN PHARMACEUTICA N.V. (BE) 2007-07-18 EP disclosed
US-20070056852-A1 Enzyme electrode sensor fuel cell and electrochemical reactor CANON KABUSHIKI KAISHA (JP) 2007-03-15 US disclosed
US-20070007132-A1 Transition metal complexes with bidentate ligand having an imidazole ring ABBOTT DIABETES CARE INC. 2007-01-11 US disclosed
US-20070007132-A1 Transition metal complexes with bidentate ligand having an imidazole ring ABBOTT DIABETES CARE INC. 2007-01-11 US disclosed
US-20060100201-A1 Inhibitors of c-fms kinase JANSSEN PHARMACEUTICA, N.V. (BE) 2006-05-11 US disclosed
WO-2006047504-A1 AROMATIC AMIDES AS INHIBITORS OF C-FMS KINASE JANSSEN PHARMACEUTICA, N.V. (BE) 2006-05-04 WO disclosed
WO-2006009324-A1 ENZYME ELECTRODE, AND DEVICE, SENSOR, FUEL CELL AND ELECTROCHEMICAL REACTOR EMPLOYING THE ENZYME ELECTRODE CANON KABUSHIKI KAISHA (JP) 2006-01-26 WO disclosed
WO-2006009328-A1 ENZYME ELECTRODE, SENSOR, FUEL CELL, AND ELECTROCHEMICAL REACTOR CANON KABUSHIKI KAISHA (JP) 2006-01-26 WO disclosed
US-4053444-A COLLOIDAL POLYAMIC ACID ELECTRODEPOSITION COMPOSITIONS AND PROCESS FOR PREPARING SAID COMPOSITIONS WESTINGHOUSE ELECTRIC CORPORATION (US) 1977-10-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060100201-A1 Inhibitors of c-fms kinase MUSK, FLT3, FES BRD4 3471/4885NISCH 4206/4885ALDH1A1 4796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.