⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4408680 | 0.88 | MEN1 (0.32) | — | |
| Ammonia Solution, Strong SCHEMBL28609530 | 0.87 | MEN1 (0.31) | — | |
| SCHEMBL25334575 | 0.72 | ALDH1A1 (0.41) | — | |
| SCHEMBL29392985 | 0.69 | MEN1 (0.35) | — | |
| SCHEMBL15486172 | 0.69 | NAALAD2 (0.32) | — | |
| SCHEMBL16317409 | 0.69 | NAALAD2 (0.38) | — | |
| SCHEMBL17502001 | 0.68 | — | — | |
| SCHEMBL16334546 | 0.65 | STING1 (0.36) | — | |
| SCHEMBL328633 | 0.65 | STING1 (0.36) | — | |
| SCHEMBL3960043 | 0.65 | GRM4 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11541122-B2 | Glucose sensitive insulins and uses thereof | ZIYLO LIMITED | 2023-01-03 | — | — | US | disclosed |
| US-20220047708-A1 | GLUCOSE SENSITIVE INSULINS AND USES THEREOF | NOVO NORDISK RESEARCH CENTRE OXFORD LIMITED (GB) | 2022-02-17 | — | — | US | disclosed |
| EP-3852873-A1 | GLUCOSE SENSITIVE INSULINS AND USES THEREOF | Ziylo Ltd (GB) | 2021-07-28 | — | — | EP | disclosed |
| WO-2020058322-A1 | GLUCOSE SENSITIVE INSULINS AND USES THEREOF | ZIYLO LTD. (GB) | 2020-03-26 | — | — | WO | disclosed |