Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL28609530 | 0.99 | MEN1 (0.31) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL21804756 | 0.88 | — | — | |
| SCHEMBL15486172 | 0.80 | NAALAD2 (0.32) | NAALAD2 | |
| SCHEMBL17502001 | 0.79 | — | — | |
| SCHEMBL25334575 | 0.75 | ALDH1A1 (0.41) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL29392985 | 0.72 | MEN1 (0.35) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL16317409 | 0.71 | NAALAD2 (0.38) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL1406359 | 0.69 | NAALAD2 (0.38) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL16334546 | 0.68 | STING1 (0.36) | ALDH1A1 | |
| SCHEMBL328633 | 0.68 | STING1 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919055-B2 | Sugar-linker-drug conjugates | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-03-20 | — | — | US | disclosed |
| US-20160045611-A1 | SUGAR-LINKER-DRUG CONJUGATES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-02-18 | — | — | US | disclosed |
| US-20160038615-A1 | SACCHARIDE CONJUGATES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-02-11 | — | — | US | disclosed |
| EP-1450822-B1 | Polyalkylene oxide conjugates of thiol-containing drugs | ENZON INC (US) | 2009-12-23 | — | — | EP | disclosed |
| WO-2006051506-A3 | CONVENIENT SYNTHESIS OF 1 --> 3 C-BRANCHED DENDRONS | UNIV AKRON (US) | 2007-06-14 | — | — | WO | disclosed |
| EP-1759713-A2 | Lock and key micelles | UNIVERSITY OF SOUTH FLORIDA (US) | 2007-03-07 | — | — | EP | disclosed |
| EP-1749516-A2 | Lock and key micelles | UNIVERSITY OF SOUTH FLORIDA (US) | 2007-02-07 | — | — | EP | disclosed |
| EP-1007011-B1 | LOCK AND KEY MICELLES | UNIV SOUTH FLORIDA (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2006051506-A2 | CONVENIENT SYNTHESIS OF 1 --> 3 C-BRANCHED DENDRONS | THE UNIVERSITY OF AKRON (US) | 2006-05-18 | — | — | WO | disclosed |
| US-7033583-B2 | Polymeric thiol-linked prodrugs | ENZON PHARMACEUTICALS, INC. (US) | 2006-04-25 | — | — | US | disclosed |
| US-6777387-B2 | REACTING A BIOLOGICALLY ACTIVE DRUG CONTAINING UNPROTECTED AMINO OR HYDROXY GROUPS WITH A POLYALKYLENE GLYCOL RESIDUE CONTAINING A REACTIVE TERMINAL GROUP | ENZON PHARMACEUTICALS, INC. | 2004-08-17 | — | — | US | disclosed |
| US-20030147844-A1 | Polymeric thiol-linked prodrugs | BELROSE PHARMA INC. | 2003-08-07 | — | — | US | disclosed |
| US-6566409-B1 | For use in radio-imaging, drug delivery, catalysis, affinity filtration for separating enantiomers | UNIVERSITY OF SOUTH FLORIDA | 2003-05-20 | — | — | US | disclosed |
| WO-2003039479-A2 | POLYMERIC THIOL-LINKED PRODRUGS | ENZON, INC. (US) | 2003-05-15 | — | — | WO | disclosed |
| US-20020015691-A1 | Terminally-branched polymeric linkers containing extension moieties and polymeric conjugates containing the same | BELROSE PHARMA INC. | 2002-02-07 | — | — | US | disclosed |
| EP-0771190-A4 | LOCK AND KEY MICELLES | UNIV SOUTH FLORIDA (US) | 2000-12-20 | — | — | EP | disclosed |
| US-6130209-A | Lock and key micelles | UNIVERSITY OF SOUTH FLORIDA (US) | 2000-10-10 | — | — | US | disclosed |
| US-5650101-A | Lock and key micelles | UNIVERSITY OF SOUTH FLORIDA (US) | 1997-07-22 | — | — | US | disclosed |
| EP-0771190-A1 | LOCK AND KEY MICELLES | UNIVERSITY OF SOUTH FLORIDA (US) | 1997-05-07 | — | — | EP | disclosed |
| WO-1996003114-A1 | LOCK AND KEY MICELLES | UNIVERSITY OF SOUTH FLORIDA (US) | 1996-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160045611-A1 | SUGAR-LINKER-DRUG CONJUGATES | FUT5, FUT6, B3GNT2 | MEN1 3709/4885ALDH1A1 37/4885CYP1A2 1019/4885 |
| US-20020015691-A1 | Terminally-branched polymeric linkers containing extension moieties and polymeric conjugates containing the same | ITGB3, ITGB4, DRD3 | MEN1 3552/4885ALDH1A1 1014/4885CYP1A2 1943/4885 |
| US-20160038615-A1 | SACCHARIDE CONJUGATES | BLM, DCLRE1A, MAN1B1 | MEN1 110/4885ALDH1A1 3629/4885CYP1A2 4776/4885 |
| US-20030147844-A1 | Polymeric thiol-linked prodrugs | MPST, TST, SHMT1 | MEN1 3800/4885ALDH1A1 171/4885CYP1A2 378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.