⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18918401 | 0.41 | — | — | |
| Water SCHEMBL8139596 | 0.40 | CASP1 (0.44) | — | |
| SCHEMBL1627704 | 0.40 | CASP1 (0.44) | — | |
| Formaldehyde SCHEMBL6550879 | 0.38 | LMNA (0.45) | — | |
| Formaldehyde SCHEMBL9861640 | 0.38 | LMNA (0.45) | — | |
| Formaldehyde SCHEMBL3301090 | 0.38 | LMNA (0.45) | — | |
| Formaldehyde SCHEMBL11786670 | 0.38 | LMNA (0.45) | — | |
| SCHEMBL25853 | 0.37 | — | — | |
| SCHEMBL8465809 | 0.37 | CASP1 (0.50) | — | |
| SCHEMBL14164523 | 0.37 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11898204-B2 | Generation of single-stranded circular DNA templates for single molecule sequencing | Roche Sequencing Solutions, Inc. (US) | 2024-02-13 | — | — | US | disclosed |
| US-20230183797-A1 | GENERATION OF SINGLE-STRANDED CIRCULAR DNA TEMPLATES FOR SINGLE MOLECULE SEQUENCING | KAPA BIOSYSTEMS, INC | 2023-06-15 | — | — | US | disclosed |
| US-20220033806-A1 | System and Method for Modular and Combinatorial Nucleic Acid Sample Preparation for Sequencing | Roche Sequencing Solutions, Inc. | 2022-02-03 | — | — | US | disclosed |
| EP-3853362-A1 | SYSTEM AND METHOD FOR MODULAR AND COMBINATORIAL NUCLEIC ACID SAMPLE PREPARATION FOR SEQUENCING | F. Hoffmann-La Roche AG (CH) | 2021-07-28 | — | — | EP | disclosed |
| CN-112805380-A | System and method for preparing modular and combinatorial nucleic acid samples for sequencing | 豪夫迈·罗氏有限公司 | 2021-05-14 | — | — | CN | disclosed |
| EP-3759241-A1 | GENERATION OF SINGLE-STRANDED CIRCULAR DNA TEMPLATES FOR SINGLE MOLECULE SEQUENCING | F. Hoffmann-La Roche AG (CH) | 2021-01-06 | — | — | EP | disclosed |
| CN-111936635-A | Generation of single stranded circular DNA templates for single molecule sequencing | 豪夫迈·罗氏有限公司 | 2020-11-13 | — | — | CN | disclosed |
| WO-2020058389-A1 | SYSTEM AND METHOD FOR MODULAR AND COMBINATORIAL NUCLEIC ACID SAMPLE PREPARATION FOR SEQUENCING | F. HOFFMANN-LA ROCHE AG (CH) | 2020-03-26 | — | — | WO | disclosed |