Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 7/20 | 0.46 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24012442 | 0.83 | HPGD (0.61) | HDAC3HDAC1ADORA3ADORA2AADORA2B | |
| Trifluoroacetic Acid SCHEMBL5903474 | 0.82 | SMN1; SMN2 (0.44) | MAPTHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13081990 | 0.78 | ADORA3 (0.62) | HDAC3HDAC1ADORA3ADORA2AADORA2B | |
| SCHEMBL13056379 | 0.77 | ADORA3 (0.55) | HDAC3HDAC1ADORA3ADORA2AADORA2B | |
| SCHEMBL13248222 | 0.75 | ADORA3 (0.56) | HDAC3HDAC1ADORA3ADORA2AADORA2B | |
| SCHEMBL13248219 | 0.75 | ADORA3 (0.55) | HDAC3HDAC1ADORA3ADORA2AADORA2B | |
| SCHEMBL13056382 | 0.74 | HDAC3 (0.50) | HDAC3HDAC1ADORA3ADORA2AADORA2B | |
| SCHEMBL13248218 | 0.74 | ADORA3 (0.54) | HDAC3HDAC1ADORA3ADORA2AADORA2B | |
| SCHEMBL8816476 | 0.71 | HPGD (0.55) | HPGDNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6028978 | 0.70 | ADORA3 (0.62) | HDAC3HDAC1ADORA3ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210349101-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | VENTANA MEDICAL SYSTEMS, INC. | 2021-11-11 | — | — | US | disclosed |
| EP-3853214-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | Ventana Medical Systems, Inc. (US) | 2021-07-28 | — | — | EP | disclosed |
| WO-2020058339-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | VENTANA MEDICAL SYSTEMS, INC. (US) | 2020-03-26 | — | — | WO | disclosed |