Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | RHOC | P08134 | 1/20 | 0.43 |
| ▸ | RHOA | P61586 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.41 |
| ▸ | CHRNG | P07510 | 2/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.41 |
| ▸ | CHRND | Q07001 | 2/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL21806100 | 0.82 | HDAC3 (0.49) | SMN1; SMN2HPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL8816224 | 0.79 | NTRK2 (0.46) | SMN1; SMN2HPGDNPC1RAB9ARHOC | |
| SCHEMBL25766759 | 0.77 | ALDH1A1 (0.61) | SMN1; SMN2HPGDALDH1A1CHRNA1CHRNG | |
| SCHEMBL17884625 | 0.77 | ALDH1A1 (0.61) | SMN1; SMN2HPGDALDH1A1CHRNA1CHRNG | |
| Trifluoroacetic Acid SCHEMBL22121275 | 0.77 | MLYCD (0.56) | SMN1; SMN2HPGDNPC1RAB9AGAA | |
| SCHEMBL27328060 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL18334635 | 0.76 | SMN1; SMN2 (0.41) | SMN1; SMN2RAB9AMAPTLMNA | |
| SCHEMBL8816476 | 0.76 | HPGD (0.55) | SMN1; SMN2HPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL14758320 | 0.74 | HPGD (0.52) | SMN1; SMN2HPGDNPC1RAB9AALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL30196351 | 0.74 | TERT (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141676-B1 | Water soluble multi-biotin-containing compounds | UNIVERSITY OF WASHINGTON (US) | 2006-11-28 | — | — | US | disclosed |
| US-20060228325-A1 | Water soluble multi-biotin-containing compounds | WILBUR D S | 2006-10-12 | — | — | US | disclosed |
| EP-1196199-A4 | WATER SOLUBLE MULTI-BIOTIN-CONTAINING COMPOUNDS | UNIV WASHINGTON (US) | 2002-06-19 | — | — | EP | disclosed |
| EP-1196199-A2 | WATER SOLUBLE MULTI-BIOTIN-CONTAINING COMPOUNDS | University of Washington (US) | 2002-04-17 | — | — | EP | disclosed |
| WO-2000072802-A2 | WATER SOLUBLE MULTI-BIOTIN-CONTAINING COMPOUNDS | UNIVERSITY OF WASHINGTON (US) | 2000-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060228325-A1 | Water soluble multi-biotin-containing compounds | BTD, HLCS, VNN1 | SMN1; SMN2 4237/4885HPGD 556/4885NPC1 3667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.