Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31158754 | 0.80 | ESR2 (0.44) | USP30GPR119MEN1KMT2AESR2 | |
| SCHEMBL21804759 | 0.80 | DDB1 (0.51) | USP30GPR119ESR2DDB1CRBN | |
| SCHEMBL19358137 | 0.79 | USP30 (0.42) | USP30GPR119MEN1KMT2AESR2 | |
| SCHEMBL24029364 | 0.77 | GPR119 (0.47) | GPR119MEN1KMT2AESR2NR1H2 | |
| SCHEMBL31159109 | 0.76 | LIPE (0.43) | GPR119MEN1KMT2AESR2DDB1 | |
| SCHEMBL38652724 | 0.75 | ESR2 (0.51) | MEN1KMT2AESR2NR1H2MAPK1 | |
| SCHEMBL31158906 | 0.75 | LIPE (0.38) | USP30GPR119MEN1KMT2AESR2 | |
| SCHEMBL25107642 | 0.74 | ESR2 (0.51) | ESR2DDB1CRBNNR1H2MAPK1 | |
| SCHEMBL31163315 | 0.74 | ESR2 (0.47) | ESR2NR1H2MAPK1HDAC1 | |
| SCHEMBL8221404 | 0.73 | DDB1 (0.55) | GPR119ESR2DDB1CRBNNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3852790-A1 | INHIBITING UBIQUITIN SPECIFIC PEPTIDASE 9X | Forma Therapeutics, Inc. (US) | 2021-07-28 | — | — | EP | disclosed |
| WO-2020061261-A1 | INHIBITING UBIQUITIN SPECIFIC PEPTIDASE 9X | FORMA THERAPEUTICS, INC. (US) | 2020-03-26 | — | — | WO | disclosed |