Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 4/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 2/20 | 0.38 |
| ▸ | F13A1 | P00488 | 1/20 | 0.38 |
| ▸ | TGM1 | P22735 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31357860 | 0.89 | ESR2 (0.51) | DDB1CRBNMAPK1NAMPTESR2 | |
| SCHEMBL31357971 | 0.89 | ESR2 (0.51) | DDB1CRBNMAPK1NAMPTESR2 | |
| SCHEMBL15103354 | 0.88 | DDB1 (0.52) | DDB1CRBNMAPK1NAMPTHDAC1 | |
| SCHEMBL30156851 | 0.88 | DDB1 (0.52) | DDB1CRBNMAPK1NAMPTHDAC1 | |
| SCHEMBL14615809 | 0.85 | ABHD6 (0.44) | DDB1CRBNNAMPTABHD6TGM2 | |
| SCHEMBL24812773 | 0.85 | DDB1 (0.49) | DDB1CRBNMAPK1NAMPTHDAC1 | |
| SCHEMBL25601626 | 0.82 | DDB1 (0.56) | DDB1CRBNMAPK1NAMPTHDAC1 | |
| SCHEMBL15893734 | 0.81 | DDB1 (0.55) | DDB1CRBNMAPK1NAMPTHDAC1 | |
| SCHEMBL8221404 | 0.81 | DDB1 (0.55) | DDB1CRBNMAPK1NAMPTHDAC1 | |
| SCHEMBL1050056 | 0.80 | DDB1 (0.41) | DDB1CRBNMAPK1NAMPTABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3852790-A1 | INHIBITING UBIQUITIN SPECIFIC PEPTIDASE 9X | Forma Therapeutics, Inc. (US) | 2021-07-28 | — | — | EP | disclosed |
| CN-113164571-A | Inhibition of ubiquitin-specific peptidase 9X | 福马治疗股份有限公司 | 2021-07-23 | — | — | CN | disclosed |
| WO-2020061261-A1 | INHIBITING UBIQUITIN SPECIFIC PEPTIDASE 9X | FORMA THERAPEUTICS, INC. (US) | 2020-03-26 | — | — | WO | disclosed |