Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 15/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 15/20 | 0.40 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31051495 | 0.85 | DGAT1 (0.53) | DGAT1HCRTR1HCRTR2 | |
| SCHEMBL31128747 | 0.85 | DGAT1 (0.53) | DGAT1HCRTR1HCRTR2 | |
| SCHEMBL22323300 | 0.84 | HCRTR1 (0.34) | HCRTR1HCRTR2GPR183 | |
| SCHEMBL21807918 | 0.80 | HCRTR1 (0.34) | HCRTR1HCRTR2 | |
| SCHEMBL22323316 | 0.79 | ACACB (0.32) | HCRTR1HCRTR2ACACB | |
| SCHEMBL21807890 | 0.78 | HSD11B1 (0.41) | HCRTR1HCRTR2POLBACACB | |
| SCHEMBL21807912 | 0.78 | OGA (0.38) | DGAT1HCRTR1HCRTR2 | |
| SCHEMBL8511076 | 0.75 | DGAT1 (0.45) | DGAT1HCRTR1HCRTR2 | |
| SCHEMBL21807952 | 0.75 | OGA (0.37) | HCRTR1HCRTR2 | |
| SCHEMBL14967815 | 0.74 | DGAT1 (0.46) | DGAT1HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3853226-A1 | O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS | Biogen MA Inc. (US) | 2021-07-28 | — | — | EP | disclosed |
| WO-2020061150-A1 | O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC. (US) | 2020-03-26 | — | — | WO | disclosed |