SCHEMBL21808822

SCHEMBL21808822

CCCCNc1ccc(C(=O)OCC)c(N(C)C)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 4/20 0.49
▸ SCN5A Q14524 2/20 0.49
▸ CYP1A2 P05177 2/20 0.49
▸ MAPK1 P28482 2/20 0.49
▸ MAOA P21397 1/20 0.49
▸ CNR1 P21554 1/20 0.49
▸ DRD4 P21917 1/20 0.49
▸ ACHE P22303 1/20 0.49
▸ HRH2 P25021 1/20 0.49
▸ HTR2A P28223 1/20 0.49
▸ HTR2C P28335 1/20 0.49
▸ NTSR1 P30989 1/20 0.49
▸ HRH1 P35367 1/20 0.49
▸ DRD3 P35462 1/20 0.49
▸ SCN1A P35498 1/20 0.49
▸ HTR2B P41595 1/20 0.49
▸ SCN7A Q01118 1/20 0.49
▸ SLC6A3 Q01959 1/20 0.49
▸ KCNH2 Q12809 1/20 0.49
▸ SCN9A Q15858 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27585203 0.99 LMNA (0.50) LMNASCN5ACYP1A2MAPK1MAOA
SCHEMBL1224840 0.89 LMNA (0.45) LMNASCN5ACYP1A2MAPK1MAOA
Hydrochloric Acid SCHEMBL28454605 0.88 LMNA (0.46) LMNASCN5ACYP1A2MAPK1MAOA
SCHEMBL6581270 0.82 KMT2A (0.42) LMNASCN5ACYP1A2MAPK1MAOA
SCHEMBL11310309 0.80 PLK1 (0.48) LMNASCN5ACYP1A2MAPK1MAOA
SCHEMBL11313529 0.80 PLK1 (0.48) LMNASCN5ACYP1A2MAPK1MAOA
SCHEMBL11315370 0.80 PLK1 (0.48) LMNASCN5ACYP1A2MAPK1MAOA
SCHEMBL11313614 0.80 PLK1 (0.48) LMNASCN5ACYP1A2MAPK1MAOA
SCHEMBL11306884 0.80 PLK1 (0.48) LMNASCN5ACYP1A2MAPK1MAOA
SCHEMBL11319758 0.80 PLK1 (0.48) LMNASCN5ACYP1A2MAPK1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3852719-A1 PHARMACEUTICAL COMPOSITION FOR TOPICAL USE COMPRISING AT LEAST ONE LOCAL ANAESTHETIC SUBSTANCE Société d'Exploitation de Produits pour les Industries Chimiques SEPPIC (FR) 2021-07-28 — — EP claimed
CN-112689503-A Pharmaceutical composition for topical use comprising at least one local anaesthetic substance 化工产品开发公司SEPPIC 2021-04-20 — — CN claimed
WO-2020058605-A1 PHARMACEUTICAL COMPOSITION FOR TOPICAL USE COMPRISING AT LEAST ONE LOCAL ANAESTHETIC SUBSTANCE SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2020-03-26 — — WO claimed
CN-117298071-A Oral cavity patch for treating dental ulcer and preparation method thereof 力品药业(厦门)股份有限公司 2023-12-29 — — CN disclosed
EP-3852719-A1 PHARMACEUTICAL COMPOSITION FOR TOPICAL USE COMPRISING AT LEAST ONE LOCAL ANAESTHETIC SUBSTANCE Société d'Exploitation de Produits pour les Industries Chimiques SEPPIC (FR) 2021-07-28 — — EP disclosed
CN-112689503-A Pharmaceutical composition for topical use comprising at least one local anaesthetic substance 化工产品开发公司SEPPIC 2021-04-20 — — CN disclosed
WO-2020058605-A1 PHARMACEUTICAL COMPOSITION FOR TOPICAL USE COMPRISING AT LEAST ONE LOCAL ANAESTHETIC SUBSTANCE SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2020-03-26 — — WO disclosed
CN-103932973-A Dental Anesthetic Comprising Tetracaine And A Vasoconstrictor For Intranasal Administration ST RENATUS LLC 2014-07-23 — — CN disclosed
CN-102421416-B Dental anesthetic for intranasal administration comprising tetracaine and a vasoconstrictor ST RENATUS LLC 2014-05-28 — — CN disclosed
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