Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | FPR1 | P21462 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30902962 | 1.00 | PTGER4 (0.53) | PTGER4ALOX15L3MBTL1HDAC6HDAC1 | |
| SCHEMBL22914198 | 0.88 | PTGER4 (0.48) | PTGER4ALOX15L3MBTL1MAPK8POLB | |
| SCHEMBL24149122 | 0.80 | ELANE (0.56) | PTGER4ALOX15L3MBTL1HDAC6MAPK8 | |
| SCHEMBL22913944 | 0.79 | PDE5A (0.42) | PTGER4MAPK8MEN1KMT2APTGS2 | |
| SCHEMBL16014218 | 0.78 | CNR1 (0.45) | MAPK8MAPTMEN1KMT2APTGS2 | |
| SCHEMBL24484019 | 0.78 | CNR1 (0.45) | ALOX15L3MBTL1MAPK8POLBMAPT | |
| SCHEMBL10273212 | 0.78 | LMNA (0.46) | PTGER4HDAC6HDAC1HDAC2MAPT | |
| SCHEMBL29670185 | 0.78 | CNR1 (0.45) | ALOX15L3MBTL1MAPK8POLBMAPT | |
| SCHEMBL22912889 | 0.77 | CNR1 (0.43) | PTGER4MAPK8FPR1FPR2PTGS2 | |
| SCHEMBL5103746 | 0.77 | CNR1 (0.44) | PTGER4MAPK8MAPTKMT2APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12084426-B2 | Indazole carboxamides as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-09-10 | — | — | US | disclosed |
| CN-112673001-B | Indazole carboxamides as kinase inhibitors | 百时美施贵宝公司 | 2024-06-25 | — | — | CN | disclosed |
| EP-3849969-B1 | INDAZOLE CARBOXAMIDES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2023-04-19 | — | — | EP | disclosed |
| US-20210309633-A1 | INDAZOLE CARBOXAMIDES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-10-07 | — | — | US | disclosed |
| EP-3849969-A1 | INDAZOLE CARBOXAMIDES AS KINASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2021-07-21 | — | — | EP | disclosed |
| CN-112673001-A | Indazole carboxamides as kinase inhibitors | 百时美施贵宝公司 | 2021-04-16 | — | — | CN | disclosed |
| WO-2020056074-A1 | INDAZOLE CARBOXAMIDES AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210309633-A1 | INDAZOLE CARBOXAMIDES AS KINASE INHIBITORS | RIPK3, RIPK1, RIPK2 | PTGER4 2886/4885ALOX15 3775/4885L3MBTL1 3330/4885 |
| US-12084426-B2 | Indazole carboxamides as kinase inhibitors | RIPK3, RIPK1, RIPK2 | PTGER4 2886/4885ALOX15 3775/4885L3MBTL1 3330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.