Triaziquone

Triaziquone

SCHEMBL21811697

C[SiH](C)Cl.O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.42
HTT P42858 2/20 0.42
TP53 P04637 1/20 0.42
STAT3 P40763 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
DNMT1 P26358 1/20 0.41
TDP2 O95551 3/20 0.34
NSD2 O96028 3/20 0.34
APAF1 O14727 2/20 0.34
HKDC1 Q2TB90 2/20 0.34
KMT2A Q03164 2/20 0.33
ATG4B Q9Y4P1 2/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
GALK1 P51570 1/20 0.33
BLM P54132 1/20 0.33
ATM Q13315 1/20 0.33
NOD2 Q9HC29 1/20 0.33
PLA2G1B P04054 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triaziquone SCHEMBL21835057 0.92 MAPT (0.44) MAPTHTTTP53STAT3SMN1; SMN2
Triaziquone SCHEMBL8303 0.88 DNMT1 (0.48) MAPTHTTTP53STAT3SMN1; SMN2
Triaziquone SCHEMBL7783197 0.86 MAPT (0.46) MAPTHTTTP53STAT3SMN1; SMN2
Triaziquone SCHEMBL149876 0.86 MAPT (0.46) MAPTHTTTP53STAT3SMN1; SMN2
Triaziquone SCHEMBL8993238 0.86 DNMT1 (0.47) MAPTHTTTP53STAT3SMN1; SMN2
Triaziquone SCHEMBL6000230 0.86 DNMT1 (0.47) MAPTHTTTP53STAT3SMN1; SMN2
Triaziquone SCHEMBL1538515 0.86 DNMT1 (0.47) MAPTHTTTP53STAT3SMN1; SMN2
Triaziquone SCHEMBL8482641 0.86 DNMT1 (0.47) MAPTHTTTP53STAT3SMN1; SMN2
Triaziquone SCHEMBL7738777 0.86 DNMT1 (0.47) MAPTHTTTP53STAT3SMN1; SMN2
Triaziquone SCHEMBL5054475 0.86 DNMT1 (0.47) MAPTHTTTP53STAT3SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3850023-A1 STAR POLYMERS HAVING A SILYL COUPLING Johannes Gutenberg-Universität Mainz (DE) 2021-07-21 EP disclosed
WO-2020053014-A1 STAR POLYMERS HAVING A SILYL COUPLING Johannes Gutenberg-Universität Mainz (DE) 2020-03-19 WO disclosed