SCHEMBL21811871

SCHEMBL21811871

COC(=O)CCc1cccc2c1Cc1ccccc1-2

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.53
RAB9A P51151 3/20 0.50
NPC1 O15118 2/20 0.50
ALDH1A1 P00352 3/20 0.47
GAA P10253 1/20 0.47
TSHR P16473 1/20 0.41
KDM4E B2RXH2 3/20 0.41
HTR2B P41595 2/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HTR7 P34969 1/20 0.41
CCNC P24863 1/20 0.40
CDK8 P49336 1/20 0.40
NOTUM Q6P988 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
DRD2 P14416 1/20 0.40
DRD4 P21917 1/20 0.40
DRD3 P35462 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21437933 0.87 PNMT (0.54) PNMTRAB9ANPC1ALDH1A1GAA
SCHEMBL28956893 0.85 RAB9A (0.47) PNMTRAB9ANPC1ALDH1A1TSHR
SCHEMBL27239133 0.85 PNMT (0.49) PNMTRAB9ANPC1ALDH1A1GAA
SCHEMBL28167227 0.83 PNMT (0.50) PNMTRAB9ANPC1ALDH1A1GAA
SCHEMBL1567123 0.82 PNMT (0.58) PNMTRAB9ANPC1ALDH1A1GAA
SCHEMBL28960306 0.81 PNMT (0.61) PNMTRAB9ANPC1ALDH1A1GAA
SCHEMBL5366733 0.79 PNMT (0.72) PNMTRAB9ANPC1ALDH1A1KDM4E
SCHEMBL21219200 0.79 PNMT (0.58) PNMTRAB9ANPC1ALDH1A1GAA
SCHEMBL27696743 0.79 PNMT (0.51) PNMTRAB9ANPC1ALDH1A1GAA
SCHEMBL28293490 0.79 RAB9A (0.46) PNMTRAB9ANPC1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118302701-A Retardation film and method for producing same 大阪燃气化学株式会社 2024-07-05 CN disclosed
CN-115551942-B Resin composition, and optical lens and optical film containing the same 三菱瓦斯化学株式会社 2023-11-10 CN disclosed
CN-116997833-A Retardation film 大阪燃气化学株式会社 2023-11-03 CN disclosed
CN-116997834-A Polarizer protective film 大阪燃气化学株式会社 2023-11-03 CN disclosed
CN-116324538-A Retardation film and method for producing same 日本瑞翁株式会社 2023-06-23 CN disclosed
CN-115877499-A Phase difference plate, circularly polarizing plate, and image display device 富士胶片株式会社 2023-03-31 CN disclosed
CN-112912429-B Solid additive, resin composition, and method for producing same 大阪燃气化学有限公司 2023-03-28 CN disclosed
CN-115551942-A Resin composition, and optical lens and optical film each containing the same 三菱瓦斯化学株式会社 2022-12-30 CN disclosed
CN-109642962-B Optical lens 三菱瓦斯化学株式会社 2022-07-08 CN disclosed
WO-2022070729-A1 PHASE DIFFERENCE FILM AND PRODUCTION METHOD THEREOF 日本ゼオン株式会社 2022-04-07 WO disclosed
CN-109791245-B Optical film, retardation film, and polarizing plate 三菱瓦斯化学株式会社 2021-06-15 CN disclosed
CN-112912429-A Solid additive, resin composition, and method for producing same 大阪燃气化学有限公司 2021-06-04 CN disclosed
CN-112673292-A Base material for surface protection film, surface protection film using the same, and optical film with surface protection film 日东电工株式会社 2021-04-16 CN disclosed
WO-2020085476-A1 SOLID ADDITIVE, RESIN COMPOSITION, METHOD FOR PRODUCING SOLID ADDITIVE AND METHOD FOR PRODUCING RESIN COMPOSITION 大阪ガスケミカル株式会社 2020-04-30 WO disclosed
WO-2020054135-A1 SURFACE PROTECTION FILM BASE MATERIAL, SURFACE PROTECTION FILM USING SURFACE PROTECTION FILM BASE MATERIAL, AND OPTICAL FILM HAVING SURFACE PROTECTION FILM 日東電工株式会社 2020-03-19 WO disclosed
CN-110862664-A Base material for surface protection film, method for producing the base material, and surface protection film using the base material 日东电工株式会社 2020-03-06 CN disclosed
CN-1232488-C 2,7-aryl-9-substituted fluorene and oligomer and polymer of 9-substituted fluorene DOW CHEMICAL CO (US) 2005-12-21 CN disclosed
CN-1229415-C Oligomers and polymers of 2, 7-aryl-9-substituted fluorenes and 9-substituted fluorenes DOW CHEMICAL CO (US) 2005-11-30 CN disclosed
CN-1376658-A 2,7-aryl-9-substituted fluorene and oligomer and polymer of 9-substituted fluorene DOW CHEMICAL CO (US) 2002-10-30 CN disclosed
CN-1192223-A Oligomers and polymers of 2, 7-aryl-9-substituted fluorenes and 9-substituted fluorenes DOW CHEMICAL CO (US) 1998-09-02 CN disclosed