Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.38 |
| ▸ | MMP13 | P45452 | 3/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440479 | 0.78 | MMP1 (0.35) | MMP1MMP13MMP2MMP9MEN1 | |
| SCHEMBL1058191 | 0.77 | MMP1 (0.35) | MMP1MMP13MMP2MMP9MEN1 | |
| SCHEMBL20679753 | 0.77 | MMP13 (0.43) | MMP1MMP13MMP2MMP9MEN1 | |
| SCHEMBL1584869 | 0.73 | HSP90AA1 (0.38) | MEN1KMT2ALMNAALDH1A1HTT | |
| SCHEMBL21812608 | 0.72 | CHEK1 (0.40) | MEN1KMT2AALDH1A1L3MBTL1CNR2 | |
| SCHEMBL702921 | 0.70 | GRM5 (0.32) | MEN1KMT2ALMNAALDH1A1L3MBTL1 | |
| SCHEMBL67697 | 0.70 | MEN1 (0.42) | MEN1KMT2ALMNAALDH1A1HTT | |
| SCHEMBL4700565 | 0.69 | CNR2 (0.31) | CNR2 | |
| SCHEMBL1284719 | 0.68 | MEN1 (0.39) | MEN1KMT2ALMNAALDH1A1HTT | |
| SCHEMBL1684422 | 0.67 | MEN1 (0.55) | MEN1KMT2ALMNAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020064175-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | ANTABIO SAS (FR) | 2020-04-02 | — | — | WO | disclosed |
| EP-3628672-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | Antabio SAS (FR) | 2020-04-01 | — | — | EP | disclosed |