Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.43 |
| ▸ | RARA | P10276 | 3/20 | 0.43 |
| ▸ | RARG | P13631 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.35 |
| ▸ | KDM6B | O15054 | 3/20 | 0.35 |
| ▸ | KDM4A | O75164 | 3/20 | 0.35 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.35 |
| ▸ | HIF1AN | Q9NWT6 | 3/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.35 |
| ▸ | KDM3B | Q7LBC6 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263726 | 0.85 | TSHR (0.42) | ALDH1A1KMT2AKDM4EKDM5BKDM6B | |
| SCHEMBL21804494 | 0.85 | TSHR (0.49) | RARBRARARARGALDH1A1KMT2A | |
| SCHEMBL21815219 | 0.79 | GRM4 (0.36) | RARBRARARARGALDH1A1KDM4E | |
| SCHEMBL21804283 | 0.78 | TSHR (0.47) | ALDH1A1KMT2AKDM4ETSHRHSD17B10 | |
| SCHEMBL21803940 | 0.76 | TSHR (0.45) | ALDH1A1KMT2AKDM4EPOLBTSHR | |
| SCHEMBL17786779 | 0.73 | TSHR (0.49) | ALDH1A1KMT2AKDM4EPOLBTSHR | |
| SCHEMBL21815216 | 0.73 | CCNE2 (0.37) | ALDH1A1TSHRHTTSMN1; SMN2MAPK1 | |
| SCHEMBL18018335 | 0.72 | TDP1 (0.47) | ALDH1A1KDM4EPOLBKDM6BKDM4A | |
| Phthalic Acid SCHEMBL3684062 | 0.72 | ALDH1A1 (0.58) | ALDH1A1KMT2APTK2BKDM4EPOLB | |
| SCHEMBL23009908 | 0.72 | KDM6B (0.40) | ALDH1A1KDM4EKDM5BKDM6BKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3856188-A1 | AMINOPYRIMIDINE COMPOUND | Cardurion Pharmaceuticals, LLC (US) | 2021-08-04 | — | — | EP | disclosed |
| WO-2020068854-A1 | AMINOPYRIMIDINE COMPOUND | CARDURION PHARMACEUTICALS, LLC (US) | 2020-04-02 | — | — | WO | disclosed |