SCHEMBL218153

SCHEMBL218153

CCCCCCCCCCCCCOCCCC(N)CCN

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.46
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
THRB P10828 1/20 0.44
MAPT P10636 1/20 0.44
DNM1 Q05193 4/20 0.41
S1PR2 O95136 5/20 0.41
S1PR1 P21453 5/20 0.41
S1PR3 Q99500 5/20 0.41
S1PR4 O95977 4/20 0.41
CYP3A4 P08684 1/20 0.41
PLA2G1B P04054 1/20 0.40
PLA2G2A P14555 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8992522 1.00 HTT (0.46) HTTMEN1KMT2ATHRBMAPT
SCHEMBL1526068 1.00 HTT (0.46) HTTMEN1KMT2ATHRBMAPT
SCHEMBL221460 1.00 HTT (0.46) HTTMEN1KMT2ATHRBMAPT
SCHEMBL8992550 1.00 HTT (0.46) HTTMEN1KMT2ATHRBMAPT
SCHEMBL452976 1.00 HTT (0.46) HTTMEN1KMT2ATHRBMAPT
SCHEMBL10908552 1.00 HTT (0.46) HTTMEN1KMT2ATHRBMAPT
SCHEMBL8992540 1.00 HTT (0.46) HTTMEN1KMT2ATHRBMAPT
SCHEMBL1525901 1.00 HTT (0.46) HTTMEN1KMT2ATHRBMAPT
SCHEMBL10908833 1.00 HTT (0.46) HTTMEN1KMT2ATHRBMAPT
SCHEMBL9807776 0.96 HTT (0.46) HTTMEN1KMT2ATHRBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1581325-A1 SOLUBILIZED DEFOAMERS FOR CEMENTITIOUS COMPOSITIONS Construction Research & Technology GmbH (DE) 2005-10-05 EP claimed
US-6875801-B2 Solubilized defoamers for cementitious compositions CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2005-04-05 US claimed
WO-2004056445-A1 SOLUBILIZED DEFOAMERS FOR CEMENTITIOUS COMPOSITIONS CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2004-07-08 WO claimed
US-20030187101-A1 Solubilized defoamers for cementitious compositions MBT HOLDING AG 2003-10-02 US claimed
US-4498908-A Liquid fuel composition containing reaction product of tetrahydropyrimidines MOBIL OIL CORPORATION (US) 1985-02-12 US claimed
US-4495076-A Lubricating oil composition containing reaction product of tetrahydropyrimidines MOBIL OIL CORPORATION (US) 1985-01-22 US claimed
US-4252745-A OIL AND FUEL ADDITIVES; ANTIDEPOSIT AGENTS; OXIDATION RESISTANCE; COLD RESISTANCE UOP INC. (US) 1981-02-24 US claimed
US-9212095-B2 Use of HyperBranched polyether surfactant in cementitious systems CONSTRUCTION RESEARCH & TECHNOLOGY, GMBH (DE) 2015-12-15 US disclosed
WO-2012113765-A1 USE OF HYPERBRANCHED POLYETHER SURFACTANT IN CEMENTITIOUS SYSTEMS CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2012-08-30 WO disclosed
US-20120214901-A1 Use of HyperBranched Polyether Surfactant in Cementitious Systems CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2012-08-23 US disclosed
US-8088842-B2 Solubilized defoamers for cementitious compositions CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2012-01-03 US disclosed
US-20050257720-A1 Solubilized defoamers for cementitious compositions CONSTRUCTION RESEARCH & TECHNOLOGY GMBH 2005-11-24 US disclosed
EP-1581325-A1 SOLUBILIZED DEFOAMERS FOR CEMENTITIOUS COMPOSITIONS Construction Research & Technology GmbH (DE) 2005-10-05 EP disclosed
US-4522632-A FRICTION REDUCING ANTIOXZIDANTS, ANTIRUST ADDITIVES MOBIL OIL CORPORATION (US) 1985-06-11 US disclosed
US-4508541-A DETERGENTS TEXACO INC. (US) 1985-04-02 US disclosed
US-4498908-A Liquid fuel composition containing reaction product of tetrahydropyrimidines MOBIL OIL CORPORATION (US) 1985-02-12 US disclosed
US-4495076-A Lubricating oil composition containing reaction product of tetrahydropyrimidines MOBIL OIL CORPORATION (US) 1985-01-22 US disclosed
US-4329505-A Preparation of polymeric reaction products of alkoxyalkylamines and epihalohydrins UOP INC. (US) 1982-05-11 US disclosed
US-4284415-A EPIHALOHYDRIN ALKOXYALKYLAMINE REACTION PRODUCT ANTIDEPOSIT AGENT UOP INC. (US) 1981-08-18 US disclosed
US-4252745-A OIL AND FUEL ADDITIVES; ANTIDEPOSIT AGENTS; OXIDATION RESISTANCE; COLD RESISTANCE UOP INC. (US) 1981-02-24 US disclosed