SCHEMBL8992550

SCHEMBL8992550

CCCCCCCCCOCCCC(N)CCN

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.46
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
THRB P10828 1/20 0.44
MAPT P10636 1/20 0.44
DNM1 Q05193 4/20 0.41
S1PR2 O95136 5/20 0.41
S1PR1 P21453 5/20 0.41
S1PR3 Q99500 5/20 0.41
S1PR4 O95977 4/20 0.41
CYP3A4 P08684 1/20 0.41
PLA2G1B P04054 1/20 0.40
PLA2G2A P14555 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL218153 1.00 HTT (0.46) HTTMEN1KMT2ATHRBMAPT
SCHEMBL8992522 1.00 HTT (0.46) HTTMEN1KMT2ATHRBMAPT
SCHEMBL1526068 1.00 HTT (0.46) HTTMEN1KMT2ATHRBMAPT
SCHEMBL221460 1.00 HTT (0.46) HTTMEN1KMT2ATHRBMAPT
SCHEMBL452976 1.00 HTT (0.46) HTTMEN1KMT2ATHRBMAPT
SCHEMBL10908552 1.00 HTT (0.46) HTTMEN1KMT2ATHRBMAPT
SCHEMBL8992540 1.00 HTT (0.46) HTTMEN1KMT2ATHRBMAPT
SCHEMBL1525901 1.00 HTT (0.46) HTTMEN1KMT2ATHRBMAPT
SCHEMBL10908833 1.00 HTT (0.46) HTTMEN1KMT2ATHRBMAPT
SCHEMBL9807776 0.96 HTT (0.46) HTTMEN1KMT2ATHRBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5538653-A ADDING A REACTION PRODUCT OF A NITROGEN HETEROCYCLE, AN AMINE, A DICARBONYL COMPOUND AND, OPTIONALLY, A CARBOXYL COMPOUND MOBIL OIL CORPORATION (US) 1996-07-23 US claimed
US-5482521-A REACTION PRODUCT OF TRIAZOLE COMPOUND, CARBONYL COMPOUND, AMINE AND CARBOXYLIC ACID MOBIL OIL CORPORATION (US) 1996-01-09 US claimed
US-5538653-A ADDING A REACTION PRODUCT OF A NITROGEN HETEROCYCLE, AN AMINE, A DICARBONYL COMPOUND AND, OPTIONALLY, A CARBOXYL COMPOUND MOBIL OIL CORPORATION (US) 1996-07-23 US disclosed
US-5482521-A REACTION PRODUCT OF TRIAZOLE COMPOUND, CARBONYL COMPOUND, AMINE AND CARBOXYLIC ACID MOBIL OIL CORPORATION (US) 1996-01-09 US disclosed
US-5407592-A Lubricant comprising reaction product of aldehyde, benzotriazole derivative, and polyetheramine MOBIL OIL CORPORATION (US) 1995-04-18 US disclosed
US-4613343-A FUEL ADDITIVES, FRICTION RESISTANCE MOBIL OIL CORPORATION (US) 1986-09-23 US disclosed
US-4556497-A N-Alkoxyalkylenediamine diamides and lubricants containing same MOBIL OIL CORPORATION (US) 1985-12-03 US disclosed
US-4537692-A Etherdiamine borates and lubricants containing same MOBIL OIL CORPORATION (US) 1985-08-27 US disclosed
US-4532056-A Product of reacting diamine, boron-containing compound, acylsarcosine MOBIL OIL CORPORATION (US) 1985-07-30 US disclosed
US-4522632-A FRICTION REDUCING ANTIOXZIDANTS, ANTIRUST ADDITIVES MOBIL OIL CORPORATION (US) 1985-06-11 US disclosed