SCHEMBL452976

SCHEMBL452976

CCCCCCCCCCCCCCOCCCC(N)CCN

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.46
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
THRB P10828 1/20 0.44
MAPT P10636 1/20 0.44
DNM1 Q05193 4/20 0.41
S1PR2 O95136 5/20 0.41
S1PR1 P21453 5/20 0.41
S1PR3 Q99500 5/20 0.41
S1PR4 O95977 4/20 0.41
CYP3A4 P08684 1/20 0.41
PLA2G1B P04054 1/20 0.40
PLA2G2A P14555 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL218153 1.00 HTT (0.46) HTTMEN1KMT2ATHRBMAPT
SCHEMBL8992522 1.00 HTT (0.46) HTTMEN1KMT2ATHRBMAPT
SCHEMBL1526068 1.00 HTT (0.46) HTTMEN1KMT2ATHRBMAPT
SCHEMBL221460 1.00 HTT (0.46) HTTMEN1KMT2ATHRBMAPT
SCHEMBL8992550 1.00 HTT (0.46) HTTMEN1KMT2ATHRBMAPT
SCHEMBL10908552 1.00 HTT (0.46) HTTMEN1KMT2ATHRBMAPT
SCHEMBL8992540 1.00 HTT (0.46) HTTMEN1KMT2ATHRBMAPT
SCHEMBL1525901 1.00 HTT (0.46) HTTMEN1KMT2ATHRBMAPT
SCHEMBL10908833 1.00 HTT (0.46) HTTMEN1KMT2ATHRBMAPT
SCHEMBL9807776 0.96 HTT (0.46) HTTMEN1KMT2ATHRBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11535807-B2 Reduced friction lubricants comprising magnesium detergents and/or overbased magnesium detergents and molybdenum based friction modifiers LANXESS CORPORATION (US) 2022-12-27 US claimed
US-11466227-B2 Synergy and enhanced performance retention with organic and molybdenum based friction modifier combination LANXESS CORPORATION (US) 2022-10-11 US claimed
EP-3710566-B1 REDUCED FRICTION LUBRICANTS COMPRISING MAGNESIUM DETERGENTS AND/OR OVERBASED MAGNESIUM DETERGENTS AND MOLYBDENUM BASED FRICTION MODIFIERS LANXESS CORP (US) 2021-08-11 EP claimed
US-20200354644-A1 REDUCED FRICTION LUBRICANTS COMPRISING MAGNESIUM DETERGENTS AND/OR OVERBASED MAGNESIUM DETERGENTS AND MOLYBDENUM BASED FRICTION MODIFIERS LANXESS SOLUTIONS US INC. (US) 2020-11-12 US claimed
EP-3710566-A1 REDUCED FRICTION LUBRICANTS COMPRISING MAGNESIUM DETERGENTS AND/OR OVERBASED MAGNESIUM DETERGENTS AND MOLYBDENUM BASED FRICTION MODIFIERS LANXESS Solutions US Inc. (US) 2020-09-23 EP claimed
EP-3697874-A1 SYNERGY AND ENHANCED PERFORMANCE RETENTION WITH ORGANIC AND MOLYBDENUM BASED FRICTION MODIFIER COMBINATION Lanxess Solutions US Inc. (US) 2020-08-26 EP claimed
US-20200255763-A1 Synergy and Enhanced Performance Retention With Organic and Molybdenum Based Friction Modifier Combination LANXESS SOLUTIONS US INC. (US) 2020-08-13 US claimed
CN-110914392-A Synergistic and enhanced performance retention with organic friction modifier and molybdenum-based friction modifier combinations 朗盛解决方案美国公司 2020-03-24 CN claimed
WO-2019079170-A1 SYNERGY AND ENHANCED PERFORMANCE RETENTION WITH ORGANIC AND MOLYBDENUM BASED FRICTION MODIFIER COMBINATION LANXESS SOLUTIONS US INC. (US) 2019-04-25 WO claimed
US-20130149274-A1 COMPOSITIONS AND METHODS FOR SEALING THE SURFACE OF KERATINOUS SUBSTRATES L'OREAL S.A. (FR) 2013-06-13 US claimed
WO-2000053703-A1 CYCLIC THIOUREA ADDITIVES FOR LUBRICANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2000-09-14 WO claimed
US-6103674-A Oil-soluble molybdenum multifunctional friction modifier additives for lubricant compositions UNIROYAL CHEMICAL COMPANY, INC. (US) 2000-08-15 US claimed
CN-1260826-A Alkaline ether amine conveyor lubricant ECOLAB INC (US) 2000-07-19 CN claimed
EP-0990018-A1 ALKALINE ETHER AMINE CONVEYOR LUBRICANT ECOLAB INC. (US) 2000-04-05 EP claimed
US-5935913-A EXTREME PRESSURE LUBRICANTS; ASHLESS AND NONPHOSPHORUS, ANTIWEAR, ANTIFATIGUE UNIROYAL CHEMICAL COMPANY, INC. (US) 1999-08-10 US claimed
US-5932526-A CONCENTRATE MIXTURE TO BE DILUTED WITH WATER FOR USE WITHOUT FORMING INSOLUBLE PRECIPITATES AND COMPRISING ALKYLOXYALKYL MONO- OR DIAMINE AND SOLUBILIZING SURFACTANT; FOOD PROCESSING CONVEYORS, ANTIFOULING AGENTS ECOLAB, INC. (US) 1999-08-03 US claimed
US-5863874-A FOR MECHANIZED CONVEYOR SYSTEMS THAT TRANSPORT BEVERAGES, FOODS; NON-PRECIPITATING IN HARD WATER, ANTIMICROBIAL AGENTS REDUCE SLIME FROM SPILLAGE ON CONVEYOR; COMPATIBLE WITH POLYETHYLENE TEREPHTHALATE CONTAINERS ECOLAB INC. (US) 1999-01-26 US claimed
WO-1998059023-A1 ALKALINE ETHER AMINE CONVEYOR LUBRICANT ECOLAB INC. (US) 1998-12-30 WO claimed
EP-0847437-A1 ALKYL ETHER AMINE CONVEYOR LUBRICANT ECOLAB INC. (US) 1998-06-17 EP claimed
WO-1997045508-A1 ALKYL ETHER AMINE CONVEYOR LUBRICANT ECOLAB INC. (US) 1997-12-04 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130149274-A1 COMPOSITIONS AND METHODS FOR SEALING THE SURFACE OF KERATINOUS SUBSTRATES KRT18, PLOD3, DDC HTT 2957/4885MEN1 3756/4885KMT2A 563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.