SCHEMBL21815786

SCHEMBL21815786

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nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4650492 0.91 MEN1 (0.33) MEN1ALDH1A1TSHRKMT2A
SCHEMBL3410926 0.91 MEN1 (0.33) MEN1ALDH1A1TSHRKMT2A
SCHEMBL4552520 0.91 MEN1 (0.33) MEN1ALDH1A1TSHRKMT2A
SCHEMBL21815627 0.91 MEN1 (0.33) MEN1ALDH1A1TSHRKMT2A
SCHEMBL21815659 0.91 MEN1 (0.33) MEN1ALDH1A1TSHRKMT2A
SCHEMBL11863747 0.91 TSHR (0.43) MEN1ALDH1A1TSHRKMT2A
SCHEMBL7519407 0.91 MEN1 (0.33) MEN1ALDH1A1TSHRKMT2A
SCHEMBL9081703 0.91 MEN1 (0.33) MEN1ALDH1A1TSHRKMT2A
SCHEMBL3672952 0.91 MEN1 (0.33) MEN1ALDH1A1TSHRKMT2A
SCHEMBL9856241 0.91 MEN1 (0.33) MEN1ALDH1A1TSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12594345-B2 Degradable hyaluronic acid hydrogels ASCENDIS PHARMA A/S (DK) 2026-04-07 US disclosed
US-20210338834-A1 DEGRADABLE HYALURONIC ACID HYDROGELS ASCENDIS PHARMA A/S (DK) 2021-11-04 US disclosed
US-20210330798-A1 TREATMENT OF INFECTIONS ASCENDIS PHARMA A/S (DK) 2021-10-28 US disclosed
EP-3856255-A1 TREATMENT OF INFECTIONS Ascendis Pharma A/S (DK) 2021-08-04 EP disclosed
EP-3856257-A1 DEGRADABLE HYALURONIC ACID HYDROGELS Ascendis Pharma A/S (DK) 2021-08-04 EP disclosed
WO-2020064844-A1 TREATMENT OF INFECTIONS ASCENDIS PHARMA A/S (DK) 2020-04-02 WO disclosed
WO-2020064847-A1 DEGRADABLE HYALURONIC ACID HYDROGELS ASCENDIS PHARMA A/S (DK) 2020-04-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210338834-A1 DEGRADABLE HYALURONIC ACID HYDROGELS CD44, HPSE, MMP13 MEN1 2545/4885ALDH1A1 101/4885TSHR 1264/4885
US-12594345-B2 Degradable hyaluronic acid hydrogels CD44, H1-0, MMP1 MEN1 2382/4885ALDH1A1 210/4885TSHR 493/4885
US-20210330798-A1 TREATMENT OF INFECTIONS H1-10, PM20D2, ELANE MEN1 1654/4885ALDH1A1 1667/4885TSHR 3454/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.