Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | HCAR2 | Q8TDS4 | 9/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ACLY | P53396 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21819809 | 0.92 | KDM4E (0.56) | KDM4EHCAR2MEN1LMNAKMT2A | |
| SCHEMBL21819804 | 0.89 | ACLY (0.58) | KDM4EMEN1LMNAKMT2AHPGD | |
| SCHEMBL19512040 | 0.89 | HCAR2 (0.65) | HCAR2MEN1KMT2AACLY | |
| SCHEMBL19512011 | 0.89 | MEN1 (0.49) | KDM4EHCAR2MEN1LMNAKMT2A | |
| SCHEMBL19512120 | 0.88 | KDM4E (0.49) | KDM4EHCAR2MEN1LMNAKMT2A | |
| SCHEMBL19512108 | 0.82 | HCAR2 (0.65) | HCAR2TRPV1 | |
| SCHEMBL21819805 | 0.81 | POLB (0.54) | KDM4EHCAR2MEN1LMNAKMT2A | |
| SCHEMBL19512102 | 0.81 | KDM4E (0.47) | KDM4EHCAR2MEN1LMNAKMT2A | |
| SCHEMBL19511947 | 0.80 | HCAR2 (0.56) | KDM4EHCAR2ACLYALDH1A1 | |
| SCHEMBL19512028 | 0.80 | KDM4E (0.49) | KDM4EHCAR2MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3239133-B1 | DREAM NEURONAL CALCIUM SENSOR-MODULATING COMPOUNDS, AND THERAPEUTIC USES THEREOF | CONSEJO SUPERIOR INVESTIGACION (ES) | 2020-04-01 | — | — | EP | claimed |
| EP-3239133-B1 | DREAM NEURONAL CALCIUM SENSOR-MODULATING COMPOUNDS, AND THERAPEUTIC USES THEREOF | CONSEJO SUPERIOR INVESTIGACION (ES) | 2020-04-01 | — | — | EP | disclosed |