Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.48 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.47 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21819805 | 0.91 | POLB (0.54) | ACLYPOLBMEN1LMNAKMT2A | |
| SCHEMBL21819802 | 0.89 | KDM4E (0.56) | ACLYMEN1LMNAKMT2AKDM4E | |
| SCHEMBL19512125 | 0.89 | ACLY (0.74) | ACLYMEN1LMNAKMT2AKDM4E | |
| SCHEMBL19512104 | 0.87 | LMNA (0.50) | ACLYPOLBMEN1LMNAKMT2A | |
| SCHEMBL19511957 | 0.87 | MEN1 (0.50) | ACLYPOLBMEN1LMNAKMT2A | |
| SCHEMBL22000651 | 0.86 | ACLY (0.78) | ACLYPOLBMEN1LMNAKMT2A | |
| SCHEMBL19512023 | 0.85 | MEN1 (0.60) | POLBMEN1LMNAKMT2AKDM4E | |
| SCHEMBL19512124 | 0.81 | ACLY (0.60) | ACLYMEN1LMNAKMT2AKDM4E | |
| SCHEMBL21819809 | 0.81 | KDM4E (0.56) | MEN1LMNAKMT2AKDM4EMAPT | |
| SCHEMBL19512025 | 0.80 | KDM4E (0.44) | POLBMEN1LMNAKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3239133-B1 | DREAM NEURONAL CALCIUM SENSOR-MODULATING COMPOUNDS, AND THERAPEUTIC USES THEREOF | CONSEJO SUPERIOR INVESTIGACION (ES) | 2020-04-01 | — | — | EP | claimed |
| EP-3239133-B1 | DREAM NEURONAL CALCIUM SENSOR-MODULATING COMPOUNDS, AND THERAPEUTIC USES THEREOF | CONSEJO SUPERIOR INVESTIGACION (ES) | 2020-04-01 | — | — | EP | disclosed |