⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15160264 | 0.86 | — | — | |
| SCHEMBL26318602 | 0.86 | — | — | |
| SCHEMBL15786557 | 0.86 | — | — | |
| SCHEMBL12650148 | 0.79 | MEN1 (0.31) | — | |
| SCHEMBL26236754 | 0.73 | LMNA (0.35) | — | |
| SCHEMBL26081754 | 0.72 | LMNA (0.33) | — | |
| SCHEMBL21103849 | 0.72 | — | — | |
| SCHEMBL12169471 | 0.72 | — | — | |
| SCHEMBL15159934 | 0.72 | — | — | |
| SCHEMBL26316521 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502144-A | HYDROXY TERMINATED POLYORGANOSILOXANES AND CROSSLINKING AGENTS, CATALYSTS AND PROMOTERS OF FORMAMIDES | UNIVERSITY OF CINCINNATI (US) | 1996-03-26 | — | — | US | claimed |
| EP-2151480-B1 | Oily surface adhesive room temperature curing type organopolysiloxane composition and seal | SHINETSU CHEMICAL CO (JP) | 2014-04-30 | — | — | EP | disclosed |
| US-8088852-B2 | Oily surface adhesive room temperature curing type organopolysiloxane composition and seal | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-01-03 | — | — | US | disclosed |
| US-7902290-B2 | Inhibition/reduction in discoloration of diorganopolysiloxane compositions | DOW CORNING TORAY COMPANY, LTD. (JP) | 2011-03-08 | — | — | US | disclosed |
| EP-1709121-B1 | INHIBITION/REDUCTION IN DISCOLORATION OF DIORGANOPOLYSILOXANE COMPOSITIONS | DOW CORNING TORAY CO LTD (JP) | 2010-12-15 | — | — | EP | disclosed |
| US-20100036034-A1 | OILY SURFACE ADHESIVE ROOM TEMPERATURE CURING TYPE ORGANOPOLYSILOXANE COMPOSITION AND SEAL | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-02-11 | — | — | US | disclosed |
| EP-2151480-A1 | Oily surface adhesive room temperature curing type organopolysiloxane composition and seal | Shin-Etsu Chemical Co., Ltd. (JP) | 2010-02-10 | — | — | EP | disclosed |
| US-20090064960-A1 | ONE-PART SEAL MATERIAL COMPOSITION CURABLE AT AMBIENT TEMPERATURE, AND INTAKE MANIFOLD USING THE SAME | HONDA MOTOR CO., LTD. (JP) | 2009-03-12 | — | — | US | disclosed |
| US-20070219297-A1 | Inhibition/Reduction in Discoloration of Diorganopolysiloxane Compositions | DOW CORNING TORAY COMPANY, LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| EP-1709121-A1 | INHIBITION/REDUCTION IN DISCOLORATION OF DIORGANOPOLYSILOXANE COMPOSITIONS | Dow Corning Toray Co., Ltd. (JP) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005063891-A1 | INHIBITION/REDUCTION IN DISCOLORATION OF DIORGANOPOLYSILOXANE COMPOSITIONS | DOW CORNING TORAY CO., LTD. (JP) | 2005-07-14 | — | — | WO | disclosed |
| EP-1104787-B1 | Room temperature curable silicone rubber composition | DOW CORNING TORAY SILICONE (JP) | 2004-05-12 | — | — | EP | disclosed |
| US-6713546-B2 | LIQUID GASKET (FIPG); ADHESIVE PROPERTY AND CHEMICAL RESISTANCE ALSO FOR AN AUTOMOBILE MAGNESIUM ALLOY MATERIAL SINGLE BODY, AND BEING ABLE TO BE USED ALSO FOR CAST IRON AND ALUMINUM MEMBERS; DURABILITY | THREE BOND CO., LTD. (JP) | 2004-03-30 | — | — | US | disclosed |
| US-20030162928-A1 | One-pack room temperature-curable sealant composition for automobile | THREE BOND CO., LTD. (JP) | 2003-08-28 | — | — | US | disclosed |
| EP-1104787-A2 | Room temperature curable silicone rubber composition | Dow Corning Toray Silicone Co., Ltd. (JP) | 2001-06-06 | — | — | EP | disclosed |
| US-5502144-A | HYDROXY TERMINATED POLYORGANOSILOXANES AND CROSSLINKING AGENTS, CATALYSTS AND PROMOTERS OF FORMAMIDES | UNIVERSITY OF CINCINNATI (US) | 1996-03-26 | — | — | US | disclosed |
| US-5424354-A | Containing dihydroxypolysiloxane, silane having at least three hydrolyzable groups, curing catalyst, ultrafine titanium oxide particles | THREE BOND CO., LTD. (JP) | 1995-06-13 | — | — | US | disclosed |
| US-5112885-A | Fumed silica treated with organosilane is filler | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1992-05-12 | — | — | US | disclosed |