SCHEMBL21821168

SCHEMBL21821168

[2H]C([2H])([2H])c1cnc(-c2ccc3c4ccccc4c4ccccc4c3c2)cc1C([2H])([2H])[2H]

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.36
LDHA P00338 1/20 0.36
RAB9A P51151 1/20 0.34
DYRK1A Q13627 2/20 0.32
PIM1 P11309 1/20 0.32
PIM3 Q86V86 1/20 0.32
PIM2 Q9P1W9 1/20 0.32
ALOX5AP P20292 1/20 0.31
FEN1 P39748 1/20 0.31
IDO1 P14902 2/20 0.30
TDO2 P48775 2/20 0.30
PSMB5 P28074 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29444276 0.86 NPC1 (0.40) NPC1LDHARAB9AIDO1TDO2
SCHEMBL21244195 0.86 NPC1 (0.40) NPC1LDHARAB9AIDO1TDO2
SCHEMBL21244199 0.85 NPC1 (0.39) NPC1LDHARAB9AIDO1TDO2
SCHEMBL26312971 0.85 NPC1 (0.42) NPC1LDHARAB9ADYRK1APIM1
SCHEMBL19713112 0.81 LDHA (0.53) NPC1LDHARAB9AIDO1TDO2
SCHEMBL23294052 0.78 LDHA (0.41) NPC1LDHARAB9ADYRK1AIDO1
SCHEMBL30129684 0.78 LDHA (0.41) NPC1LDHARAB9ADYRK1AIDO1
SCHEMBL21821176 0.78 ALOX5AP (0.32) ALOX5APFEN1
SCHEMBL22283933 0.78 LDHA (0.38) NPC1LDHARAB9AMAPT
SCHEMBL17811394 0.77 LDHA (0.40) NPC1LDHARAB9ADYRK1APIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125406-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2026-05-07 US disclosed
US-12522625-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-01-13 US disclosed
US-20230322829-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-12 US disclosed
US-11718634-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-08 US disclosed
US-20200087334-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-03-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200087334-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG NPC1 2790/4885LDHA 3517/4885RAB9A 1546/4885
US-20260125406-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES EED, CTNND1, EEF1D NPC1 1525/4885LDHA 3031/4885RAB9A 465/4885
US-20230322829-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG NPC1 2757/4885LDHA 3499/4885RAB9A 1512/4885
US-11718634-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, ICOSLG NPC1 2790/4885LDHA 3517/4885RAB9A 1546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.