SCHEMBL21821176

SCHEMBL21821176

[2H]C([2H])([2H])c1cnc(-c2ccc3c4ccccc4c4ccccc4c3c2)cc1C1([2H])CCCCC1

nearest known ligand 0.32

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 1/20 0.32
FEN1 P39748 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CAMKK1 Q8N5S9 2/20 0.31
CAMKK2 Q96RR4 2/20 0.31
SSTR3 P32745 1/20 0.30
DHODH Q02127 1/20 0.30
SGK1 O00141 1/20 0.30
AURKA O14965 1/20 0.30
SGK3 Q96BR1 1/20 0.30
SGK2 Q9HBY8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26312977 0.80 FEN1 (0.38) ALOX5APFEN1ADORA2AADORA1KDM4E
SCHEMBL21821168 0.78 NPC1 (0.36) ALOX5APFEN1
SCHEMBL20515187 0.75 ALOX5 (0.36)
SCHEMBL19434145 0.74 LDHA (0.36) ADORA2AADORA1SMN1; SMN2DHODH
SCHEMBL21821186 0.71 CHRNB2 (0.35)
SCHEMBL17516214 0.71
SCHEMBL26312971 0.70 NPC1 (0.42) ALOX5APFEN1SMN1; SMN2
SCHEMBL29444276 0.66 NPC1 (0.40) LMNASMN1; SMN2
SCHEMBL21244195 0.66 NPC1 (0.40) LMNASMN1; SMN2
SCHEMBL22134625 0.66 ALOX5AP (0.39) ALOX5APFEN1CAMKK1CAMKK2SGK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125406-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2026-05-07 US disclosed
US-12522625-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-01-13 US disclosed
US-20230322829-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-12 US disclosed
US-11718634-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-08 US disclosed
US-20200087334-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-03-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200087334-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG ALOX5AP 1952/4885FEN1 1075/4885ADORA2A 3073/4885
US-20260125406-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES EED, CTNND1, EEF1D ALOX5AP 3897/4885FEN1 3933/4885ADORA2A 2942/4885
US-20230322829-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG ALOX5AP 1906/4885FEN1 988/4885ADORA2A 2916/4885
US-11718634-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, ICOSLG ALOX5AP 1952/4885FEN1 1075/4885ADORA2A 3073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.