SCHEMBL21821186

SCHEMBL21821186

[2H]C([2H])([2H])c1cnc(Cl)cc1C1([2H])CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.35
CHRNA4 P43681 1/20 0.35
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31635885 0.84 CHRNB2 (0.33) CHRNB2CHRNA4
SCHEMBL22283931 0.84 CHRNB2 (0.33) CHRNB2CHRNA4
SCHEMBL21821122 0.73 CHRNB2 (0.41) CHRNB2CHRNA4MEN1KMT2A
SCHEMBL32681185 0.72
SCHEMBL21821176 0.71 ALOX5AP (0.32)
SCHEMBL30873781 0.69
SCHEMBL32684677 0.65
SCHEMBL28602528 0.65
SCHEMBL21482922 0.61 KMT2A (0.49) CHRNB2CHRNA4MEN1KMT2AALDH1A1
SCHEMBL20772273 0.60 CYP17A1 (0.40) CHRNB2CHRNA4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125406-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2026-05-07 US disclosed
US-12522625-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-01-13 US disclosed
US-20230322829-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-12 US disclosed
US-11718634-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-08 US disclosed
US-20200087334-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-03-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200087334-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG CHRNB2 1620/4885CHRNA4 740/4885MEN1 3885/4885
US-20260125406-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES EED, CTNND1, EEF1D CHRNB2 1232/4885CHRNA4 581/4885MEN1 4075/4885
US-20230322829-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG CHRNB2 1578/4885CHRNA4 616/4885MEN1 3976/4885
US-11718634-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, ICOSLG CHRNB2 1620/4885CHRNA4 740/4885MEN1 3885/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.