Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.70 |
| ▸ | HPGD | P15428 | 6/20 | 0.70 |
| ▸ | POLB | P06746 | 5/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | AHR | P35869 | 1/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 4/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3291896 | 0.83 | KDM4E (0.81) | ALDH1A1KDM4EHPGDPOLBMAPT | |
| SCHEMBL4211257 | 0.82 | POLB (0.79) | ALDH1A1KDM4EHPGDPOLBMAPT | |
| SCHEMBL4211253 | 0.82 | KDM4E (0.66) | ALDH1A1KDM4EHPGDPOLBMAPT | |
| SCHEMBL1718003 | 0.78 | ALDH1A1 (0.75) | ALDH1A1KDM4EHPGDPOLBMAPT | |
| SCHEMBL4215105 | 0.77 | HPGD (0.71) | ALDH1A1KDM4EHPGDPOLBMAPT | |
| SCHEMBL1718833 | 0.76 | KDM4E (1.00) | ALDH1A1KDM4EHPGDPOLBMAPT | |
| SCHEMBL4199515 | 0.76 | HPGD (0.68) | ALDH1A1KDM4EHPGDPOLBMAPT | |
| SCHEMBL4208955 | 0.73 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDPOLBMAPT | |
| SCHEMBL1718698 | 0.72 | KDM4E (0.77) | ALDH1A1KDM4EHPGDPOLBMAPT | |
| SCHEMBL25970343 | 0.72 | KDM4E (1.00) | ALDH1A1KDM4EHPGDPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9949980-B2 | Drugs to prevent HPV infection | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2018-04-24 | — | — | US | disclosed |
| US-20150297602-A1 | DRUGS TO PREVENT HPV INFECTION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-10-22 | — | — | US | disclosed |
| US-9066951-B2 | Drugs to treat HPV infection | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2015-06-30 | — | — | US | disclosed |
| US-20110165220-A1 | DRUGS TO PREVENT HPV INFECTION | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110165220-A1 | DRUGS TO PREVENT HPV INFECTION | VHL, PHF13, CDKN1A | ALDH1A1 458/4885KDM4E 101/4885HPGD 188/4885 |
| US-20150297602-A1 | DRUGS TO PREVENT HPV INFECTION | VHL, PHF13, CDKN1A | ALDH1A1 458/4885KDM4E 101/4885HPGD 188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.