Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.77 |
| ▸ | HPGD | P15428 | 6/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.77 |
| ▸ | POLB | P06746 | 1/20 | 0.74 |
| ▸ | RAB9A | P51151 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.52 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1718615 | 0.93 | KDM4E (0.68) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL1718952 | 0.91 | ALDH1A1 (0.66) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL1718891 | 0.88 | KDM4E (0.67) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL1718968 | 0.85 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL1718833 | 0.84 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL4737183 | 0.82 | TP53 (0.80) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL4731862 | 0.81 | KDM4E (0.80) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL4204723 | 0.81 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL4214025 | 0.81 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL4738065 | 0.79 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | claimed |
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | disclosed |