Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.45 |
| ▸ | NPC1 | O15118 | 9/20 | 0.45 |
| ▸ | MAPT | P10636 | 9/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25016691 | 1.00 | RAB9A (0.45) | RAB9ANPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL21822390 | 1.00 | RAB9A (0.45) | RAB9ANPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL21822340 | 0.91 | KCNQ2 (0.42) | RAB9ANPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL21822338 | 0.91 | KCNQ2 (0.42) | RAB9ANPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL25017077 | 0.91 | KCNQ2 (0.42) | RAB9ANPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL25015851 | 0.89 | PLG (0.47) | RAB9ANPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL25015847 | 0.89 | PLG (0.47) | RAB9ANPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL21822355 | 0.86 | MAPT (0.51) | RAB9ANPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL21822353 | 0.86 | MAPT (0.51) | RAB9ANPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL25015885 | 0.86 | BTK (0.39) | KMT2AMEN1ALDH1A1HPGDF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3860636-A1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | Disc Medicine, Inc. (US) | 2021-08-11 | — | — | EP | disclosed |
| CN-112996529-A | Matriptase 2 inhibitor and application thereof | 迪斯克医药公司 | 2021-06-18 | — | — | CN | disclosed |
| WO-2020072580-A1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | DISC MEDICINE, INC. (US) | 2020-04-09 | — | — | WO | disclosed |