Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.44 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21822181 | 0.91 | F10 (0.41) | F10F2ITGB3ITGA2B | |
| SCHEMBL25016802 | 0.90 | ACKR3 (0.45) | F10ACKR3F2ITGB3ITGA2B | |
| SCHEMBL21822498 | 0.87 | F10 (0.57) | F10F2 | |
| SCHEMBL25017373 | 0.84 | F10 (0.46) | F10F2ITGB3ITGA2B | |
| SCHEMBL25017861 | 0.84 | F10 (0.45) | F10F2ITGB3ITGA2B | |
| SCHEMBL25016803 | 0.82 | F10 (0.47) | F10F2ITGB3ITGA2B | |
| SCHEMBL25017234 | 0.81 | F10 (0.49) | F10F2ITGB3ITGA2B | |
| SCHEMBL25015731 | 0.80 | ST14 (0.52) | F10F2ITGB3ITGA2B | |
| SCHEMBL21822135 | 0.78 | ITGB3 (0.40) | F10F2ITGB3ITGA2B | |
| SCHEMBL25016089 | 0.76 | F10 (0.52) | F10F2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3860636-A1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | Disc Medicine, Inc. (US) | 2021-08-11 | — | — | EP | disclosed |
| WO-2020072580-A1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | DISC MEDICINE, INC. (US) | 2020-04-09 | — | — | WO | disclosed |