Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.80 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.72 |
| ▸ | TNF | P01375 | 2/20 | 0.69 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | FLT3 | P36888 | 1/20 | 0.67 |
| ▸ | CASP3 | P42574 | 1/20 | 0.67 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.66 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.66 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8289821 | 0.89 | MAPT (0.76) | TP53PDE4BTNFNOD1L3MBTL1 | |
| SCHEMBL21347432 | 0.87 | RAB9A (0.78) | TP53PDE4BTNFNOD1L3MBTL1 | |
| SCHEMBL22789485 | 0.85 | KMT2A (0.85) | TP53PDE4BTNFNOD1L3MBTL1 | |
| SCHEMBL21346818 | 0.85 | FLT3 (0.70) | TP53PDE4BTNFNOD1L3MBTL1 | |
| SCHEMBL28650118 | 0.84 | TP53 (0.72) | TP53TNFNOD1KMT2AMEN1 | |
| SCHEMBL3922433 | 0.84 | MEN1 (0.82) | TP53PDE4BL3MBTL1PDE4DNPC1 | |
| SCHEMBL5455162 | 0.84 | MAPT (0.72) | TP53PDE4BL3MBTL1PDE4DNPC1 | |
| SCHEMBL3914076 | 0.82 | MAPT (0.73) | TP53PDE4BL3MBTL1PDE4DNPC1 | |
| SCHEMBL3916246 | 0.82 | MAPT (0.78) | TP53PDE4BL3MBTL1PDE4DNPC1 | |
| SCHEMBL21347414 | 0.81 | MAPT (0.60) | TP53PDE4BTNFNOD1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9949980-B2 | Drugs to prevent HPV infection | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2018-04-24 | — | — | US | disclosed |
| US-20150297602-A1 | DRUGS TO PREVENT HPV INFECTION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-10-22 | — | — | US | disclosed |
| US-9066951-B2 | Drugs to treat HPV infection | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2015-06-30 | — | — | US | disclosed |
| US-20110165220-A1 | DRUGS TO PREVENT HPV INFECTION | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110165220-A1 | DRUGS TO PREVENT HPV INFECTION | VHL, PHF13, CDKN1A | TP53 5/4885PDE4B 1819/4885TNF 616/4885 |
| US-20150297602-A1 | DRUGS TO PREVENT HPV INFECTION | VHL, PHF13, CDKN1A | TP53 5/4885PDE4B 1819/4885TNF 616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.