Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.72 |
| ▸ | RECQL | P46063 | 3/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | APP | P05067 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.72 |
| ▸ | THRB | P10828 | 2/20 | 0.72 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.72 |
| ▸ | ELAVL3 | Q14576 | 2/20 | 0.72 |
| ▸ | IPMK | Q8NFU5 | 2/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.72 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.72 |
| ▸ | BCL9 | O00512 | 3/20 | 0.70 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.70 |
| ▸ | POLH | Q9Y253 | 4/20 | 0.69 |
| ▸ | NOX4 | Q9NPH5 | 3/20 | 0.69 |
| ▸ | USP2 | O75604 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29369747 | 1.00 | MEN1 (0.72) | MEN1KMT2AKDM4ECYP3A4RECQL | |
| SCHEMBL28415079 | 0.92 | MEN1 (0.74) | MEN1KMT2AKDM4ECYP3A4RECQL | |
| SCHEMBL27948361 | 0.90 | BCL9 (0.72) | MEN1KMT2AKDM4ECYP3A4RECQL | |
| SCHEMBL13445534 | 0.88 | ACE2 (0.69) | MEN1KMT2AKDM4ECYP3A4RECQL | |
| SCHEMBL29369818 | 0.88 | ACE2 (0.69) | MEN1KMT2AKDM4ECYP3A4RECQL | |
| SCHEMBL5126336 | 0.86 | MEN1 (0.69) | MEN1KMT2AKDM4ECYP3A4RECQL | |
| SCHEMBL9957935 | 0.85 | MEN1 (0.68) | MEN1KMT2AKDM4ECYP3A4RECQL | |
| SCHEMBL27581494 | 0.85 | MEN1 (0.79) | MEN1KMT2AKDM4ECYP3A4RECQL | |
| SCHEMBL27193648 | 0.84 | MEN1 (0.82) | MEN1KMT2AKDM4ECYP3A4RECQL | |
| Rhamnetin SCHEMBL7164573 | 0.84 | MEN1 (1.00) | MEN1KMT2AKDM4ECYP3A4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220143058-A1 | Pharmaceutical Compositions Comprising a Hydroxyethylquercetin Glucuronide | JANSSEN PHARMACEUTICA NV (BE) | 2022-05-12 | — | — | US | disclosed |
| EP-3860617-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING A HYDROXYETHYLQUERCETIN GLUCURONIDE | Janssen Pharmaceutica N.V. (BE) | 2021-08-11 | — | — | EP | disclosed |
| US-20200155584-A1 | Pharmaceutical Compositions Comprising a Hydroxyethylquercetin Glucuronide | JANSSEN PHARMACEUTICA NV (BE) | 2020-05-21 | — | — | US | disclosed |
| WO-2020070643-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING A HYDROXYETHYLQUERCETIN GLUCURONIDE | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220143058-A1 | Pharmaceutical Compositions Comprising a Hydroxyethylquercetin Glucuronide | COMT, UGT1A6, SLC6A2 | MEN1 3746/4885KMT2A 3138/4885KDM4E 1374/4885 |
| US-20200155584-A1 | Pharmaceutical Compositions Comprising a Hydroxyethylquercetin Glucuronide | COMT, UGT1A6, SLC6A2 | MEN1 3746/4885KMT2A 3138/4885KDM4E 1374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.