Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 6/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 1.00 |
| ▸ | RECQL | P46063 | 4/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | IPMK | Q8NFU5 | 3/20 | 1.00 |
| ▸ | IP6K2 | Q9UHH9 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | APP | P05067 | 2/20 | 1.00 |
| ▸ | THRB | P10828 | 2/20 | 1.00 |
| ▸ | AKR1B1 | P15121 | 2/20 | 1.00 |
| ▸ | ELAVL3 | Q14576 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | XDH | P47989 | 3/20 | 0.82 |
| ▸ | DPP4 | P27487 | 2/20 | 0.82 |
| ▸ | MAOA | P21397 | 3/20 | 0.81 |
| ▸ | NOX4 | Q9NPH5 | 3/20 | 0.80 |
| ▸ | PLG | P00747 | 2/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Rhamnetin SCHEMBL555118 | 1.00 | MEN1 (1.00) | MEN1KMT2AKDM4ERECQLHSD17B10 | |
| Rhamnetin SCHEMBL29496169 | 1.00 | MEN1 (1.00) | MEN1KMT2AKDM4ERECQLHSD17B10 | |
| Rhamnetin SCHEMBL29453025 | 1.00 | MEN1 (1.00) | MEN1KMT2AKDM4ERECQLHSD17B10 | |
| Ombuine SCHEMBL29475881 | 0.90 | XDH (1.00) | MEN1KMT2AKDM4ERECQLHSD17B10 | |
| Ombuine SCHEMBL1252211 | 0.90 | XDH (1.00) | MEN1KMT2AKDM4ERECQLHSD17B10 | |
| Ombuine SCHEMBL31516400 | 0.90 | XDH (1.00) | MEN1KMT2AKDM4ERECQLHSD17B10 | |
| SCHEMBL26936149 | 0.90 | KDM4E (0.82) | MEN1KMT2AKDM4ERECQLHSD17B10 | |
| Rhamnazin SCHEMBL29724889 | 0.90 | MEN1 (0.84) | MEN1KMT2AKDM4ERECQLHSD17B10 | |
| Rhamnazin SCHEMBL39443 | 0.90 | MEN1 (0.84) | MEN1KMT2AKDM4ERECQLHSD17B10 | |
| SCHEMBL27193648 | 0.90 | MEN1 (0.82) | MEN1KMT2AKDM4ERECQLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6555523-B1 | Such as 3',4'-diacetoxy-5,6,7-trimethoxyflavone or naringin in the treatment HIV, picornavirus, and/or respiratory virus | CASCADE ESTATES LTD. (MU) | 2003-04-29 | — | — | US | disclosed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | disclosed |