Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | RECQL | P46063 | 3/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | APP | P05067 | 2/20 | 0.68 |
| ▸ | THRB | P10828 | 2/20 | 0.68 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.68 |
| ▸ | ELAVL3 | Q14576 | 2/20 | 0.68 |
| ▸ | IPMK | Q8NFU5 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.68 |
| ▸ | BCL9 | O00512 | 3/20 | 0.65 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.65 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27919434 | 0.91 | XDH (0.63) | MEN1KMT2ACYP3A4MAPTKDM4E | |
| SCHEMBL12621081 | 0.91 | ABCB1 (0.62) | MEN1KMT2ACYP3A4MAPTKDM4E | |
| SCHEMBL14254531 | 0.89 | ACE2 (0.59) | MEN1KMT2ACYP3A4MAPTKDM4E | |
| SCHEMBL27897199 | 0.88 | MEN1 (0.78) | MEN1KMT2ACYP3A4MAPTKDM4E | |
| SCHEMBL28415079 | 0.86 | MEN1 (0.74) | MEN1KMT2ACYP3A4MAPTKDM4E | |
| SCHEMBL15228351 | 0.86 | NOX4 (0.69) | MEN1KMT2ACYP3A4MAPTKDM4E | |
| SCHEMBL5126336 | 0.85 | MEN1 (0.69) | MEN1KMT2ACYP3A4MAPTKDM4E | |
| SCHEMBL13056280 | 0.85 | MEN1 (0.52) | MEN1KMT2ACYP3A4MAPTKDM4E | |
| SCHEMBL21823965 | 0.85 | MEN1 (0.72) | MEN1KMT2ACYP3A4MAPTKDM4E | |
| SCHEMBL29369747 | 0.85 | MEN1 (0.72) | MEN1KMT2ACYP3A4MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013130020-A1 | QUERCETIN DERIVATIVES, THEIR PHARMACEUTICAL COMPOSITION AND USE | ÚSTAV EXPERIMENTÁLNEJ FARMAKOLÓGIE A TOXIKOLÓGIE SAV (SK) | 2013-09-06 | — | — | WO | disclosed |
| EP-2468741-A1 | Novel quercetin derivatives, their preparation, pharmaceutical compositions containing them and their use | Bel/Novamann International s.r.o. (SK) | 2012-06-27 | — | — | EP | disclosed |