Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid Monododecyl Ester. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 14/20 | 0.84 |
| ▸ | LPAR2 | Q9HBW0 | 10/20 | 0.84 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.84 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid Monododecyl Ester SCHEMBL27464086 | 0.98 | LPAR3 (0.81) | LPAR3LPAR2LPAR1LPAR5CYP3A4 | |
| Phosphoric Acid Monododecyl Ester SCHEMBL28288417 | 0.98 | LPAR3 (0.81) | LPAR3LPAR2LPAR1LPAR5CYP3A4 | |
| Phosphoric Acid Monododecyl Ester SCHEMBL27494134 | 0.98 | LPAR3 (0.81) | LPAR3LPAR2LPAR1LPAR5CYP3A4 | |
| Phosphoric Acid Monododecyl Ester SCHEMBL27534734 | 0.96 | LPAR3 (0.78) | LPAR3LPAR2LPAR1LPAR5 | |
| Phosphoric Acid Monododecyl Ester SCHEMBL28243095 | 0.96 | LPAR3 (0.78) | LPAR3LPAR2LPAR1LPAR5 | |
| Phosphoric Acid Monododecyl Ester SCHEMBL28863149 | 0.96 | LPAR3 (0.78) | LPAR3LPAR2LPAR1LPAR5 | |
| SCHEMBL29136 | 0.92 | LPAR3 (1.00) | LPAR3LPAR2LPAR1LPAR5CYP3A4 | |
| Phosphoric Acid Monododecyl Ester SCHEMBL9437045 | 0.92 | LPAR3 (1.00) | LPAR3LPAR2LPAR1LPAR5CYP3A4 | |
| Hexadecyl Dihydrogen Phosphate SCHEMBL63748 | 0.92 | LPAR3 (1.00) | LPAR3LPAR2LPAR1LPAR5CYP3A4 | |
| SCHEMBL22325599 | 0.92 | LPAR3 (1.00) | LPAR3LPAR2LPAR1LPAR5CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3860949-A1 | METHOD FOR PREPARING A MONOLITHIC NANOPOROUS SILICATE SOL-GEL MATERIAL | Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) | 2021-08-11 | — | — | EP | disclosed |
| WO-2020070456-A1 | METHOD FOR PREPARING A MONOLITHIC NANOPOROUS SILICATE SOL-GEL MATERIAL | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2020-04-09 | — | — | WO | disclosed |