Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid Monododecyl Ester. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 14/20 | 0.78 |
| ▸ | LPAR2 | Q9HBW0 | 11/20 | 0.78 |
| ▸ | LPAR1 | Q92633 | 8/20 | 0.78 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid Monododecyl Ester SCHEMBL28243095 | 1.00 | LPAR3 (0.78) | LPAR3LPAR2LPAR1LPAR5ENPP2 | |
| Phosphoric Acid Monododecyl Ester SCHEMBL27494134 | 0.98 | LPAR3 (0.81) | LPAR3LPAR2LPAR1LPAR5 | |
| Phosphoric Acid Monododecyl Ester SCHEMBL27464086 | 0.98 | LPAR3 (0.81) | LPAR3LPAR2LPAR1LPAR5 | |
| Phosphoric Acid Monododecyl Ester SCHEMBL28288417 | 0.98 | LPAR3 (0.81) | LPAR3LPAR2LPAR1LPAR5 | |
| Phosphoric Acid Monododecyl Ester SCHEMBL27534734 | 0.96 | LPAR3 (0.78) | LPAR3LPAR2LPAR1LPAR5ENPP2 | |
| Phosphoric Acid Monododecyl Ester SCHEMBL21824296 | 0.96 | LPAR3 (0.84) | LPAR3LPAR2LPAR1LPAR5 | |
| Phosphoric Acid Monododecyl Ester SCHEMBL28078217 | 0.90 | LPAR3 (0.88) | LPAR3LPAR2LPAR1LPAR5 | |
| SCHEMBL28337300 | 0.90 | LPAR3 (0.95) | LPAR3LPAR2LPAR1LPAR5 | |
| SCHEMBL3411900 | 0.90 | LPAR3 (0.95) | LPAR3LPAR2LPAR1LPAR5 | |
| Hexadecyl Dihydrogen Phosphate SCHEMBL61625 | 0.90 | LPAR3 (0.95) | LPAR3LPAR2LPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108431118-A | Latex composition | 日本瑞翁株式会社 | 2018-08-21 | — | — | CN | disclosed |