Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CTSV | O60911 | 3/20 | 0.40 |
| ▸ | CTSL | P07711 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2174086 | 1.00 | KMT2A (0.44) | KMT2AMAPTMEN1HPGDALDH1A1 | |
| SCHEMBL2174081 | 1.00 | KMT2A (0.44) | KMT2AMAPTMEN1HPGDALDH1A1 | |
| SCHEMBL9365132 | 0.94 | MEN1 (0.43) | KMT2AMAPTMEN1HPGDMAOB | |
| SCHEMBL29368044 | 0.87 | KMT2A (0.42) | KMT2AMAPTMEN1HPGDALDH1A1 | |
| SCHEMBL1134236 | 0.87 | KMT2A (0.42) | KMT2AMAPTMEN1HPGDALDH1A1 | |
| SCHEMBL13074414 | 0.87 | KMT2A (0.42) | KMT2AMAPTMEN1HPGDALDH1A1 | |
| SCHEMBL28138552 | 0.86 | KMT2A (0.41) | KMT2AMAPTMEN1HPGDALDH1A1 | |
| SCHEMBL28923195 | 0.82 | KMT2A (0.42) | KMT2AMAPTMEN1HPGDALDH1A1 | |
| SCHEMBL7051037 | 0.81 | ADRB2 (0.54) | MAPK1 | |
| SCHEMBL7051039 | 0.81 | ADRB2 (0.54) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2348013-A1 | Process for preparation of intermediates of arformoterol | INKE, S.A. (ES) | 2011-07-27 | — | — | EP | claimed |
| EP-2348013-A1 | Process for preparation of intermediates of arformoterol | INKE, S.A. (ES) | 2011-07-27 | — | — | EP | disclosed |