Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 17/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7051037 | 1.00 | ADRB2 (0.54) | ADRB2ADRB1ADRB3DRD2CYP3A4 | |
| SCHEMBL9360727 | 0.91 | MEN1 (0.49) | ADRB2ADRB1ADRB3ADRA1AADRA1D | |
| SCHEMBL10661432 | 0.90 | ADRB2 (0.49) | ADRB2ADRB1ADRB3CYP3A4CYP2D6 | |
| SCHEMBL3628731 | 0.90 | KMT2A (0.46) | ADRB2ADRB1ADRB3DRD2CYP3A4 | |
| SCHEMBL30835089 | 0.84 | ADRB2 (0.59) | ADRB2ADRB1ADRB3DRD2CYP3A4 | |
| SCHEMBL9360806 | 0.84 | ADRB2 (0.53) | ADRB2ADRB1ADRB3ADRA1ATSHR | |
| SCHEMBL30835103 | 0.82 | ADRB2 (0.70) | ADRB2ADRB1ADRB3DRD2CYP3A4 | |
| SCHEMBL1134236 | 0.82 | KMT2A (0.42) | MAPK1 | |
| SCHEMBL13074414 | 0.82 | KMT2A (0.42) | MAPK1 | |
| SCHEMBL29368044 | 0.82 | KMT2A (0.42) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1093450-B1 | DESFORMOTEROL AND PROCESS FOR ITS PREPARATION | SEPRACOR INC (US) | 2003-04-23 | — | — | EP | disclosed |
| US-6071971-A | FOR TREATING PULMONARY DISORDERS | SEPRACOR INC. (US) | 2000-06-06 | — | — | US | disclosed |
| US-5965622-A | BRONCHODILATORS; HIGHLY SELECTIVE BETA 2-ADRENERGIC RECEPTOR AGONIST; RESPIRATORY DISORDERS, E.G. ASTHMA, BRONCHITIS; REDUCTION OF A PROTECTED NITRO DERIVATIVE; STEREOSPECIFIC | SEPRACOR INC. (US) | 1999-10-12 | — | — | US | disclosed |