Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 15/20 | 0.68 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.61 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.61 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.61 |
| ▸ | PIK3R2 | O00459 | 2/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.42 |
| ▸ | SRC | P12931 | 6/20 | 0.40 |
| ▸ | ABL1 | P00519 | 4/20 | 0.40 |
| ▸ | HCK | P08631 | 3/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 2/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.40 |
| ▸ | PRKDC | P78527 | 2/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13829687 | 0.91 | PIK3CD (0.59) | PIK3CDPIK3CGPIK3R1CSNK1EPIK3CB | |
| SCHEMBL29651579 | 0.89 | PIK3CD (0.70) | PIK3CDPIK3CGPIK3R1CSNK1EPIK3R2 | |
| SCHEMBL11071 | 0.89 | PIK3CD (0.70) | PIK3CDPIK3CGPIK3R1CSNK1EPIK3R2 | |
| SCHEMBL11030 | 0.88 | PIK3CD (0.70) | PIK3CDPIK3CGPIK3R1CSNK1EPIK3R2 | |
| SCHEMBL29651768 | 0.88 | PIK3CD (0.70) | PIK3CDPIK3CGPIK3R1CSNK1EPIK3R2 | |
| SCHEMBL29651549 | 0.87 | PIK3CD (0.64) | PIK3CDPIK3CGPIK3R1CSNK1EPIK3R2 | |
| SCHEMBL11542 | 0.87 | PIK3CD (0.64) | PIK3CDPIK3CGPIK3R1CSNK1EPIK3R2 | |
| SCHEMBL11175 | 0.87 | PIK3CD (0.69) | PIK3CDPIK3CGPIK3R1CSNK1EPIK3R2 | |
| SCHEMBL29651632 | 0.87 | PIK3CD (0.69) | PIK3CDPIK3CGPIK3R1CSNK1EPIK3R2 | |
| SCHEMBL30012572 | 0.87 | PIK3CD (0.78) | PIK3CDPIK3CGPIK3R1CSNK1EPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120059001-A1 | NOVEL KINASE MODULATORS | INCOZEN THERAPEUTICS PVT. LTD. (IN) | 2012-03-08 | — | — | US | disclosed |
| US-20110118257-A1 | NOVEL KINASE MODULATORS | RHIZEN PHARMACEUTICALS SA (CH) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118257-A1 | NOVEL KINASE MODULATORS | PRKCA, PRKCH, PRKCB | PIK3CD 70/4885PIK3CG 99/4885PIK3R1 95/4885 |
| US-20120059001-A1 | NOVEL KINASE MODULATORS | PRKCA, PRKCH, PRKCB | PIK3CD 70/4885PIK3CG 99/4885PIK3R1 95/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.