Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.74 |
| ▸ | NAAA | Q02083 | 1/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.61 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.61 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.61 |
| ▸ | FAAH | O00519 | 2/20 | 0.61 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | PAM | P19021 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RAD52 | P43351 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25355680 | 1.00 | DGKA (0.74) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL25191417 | 1.00 | DGKA (0.74) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL24573011 | 1.00 | DGKA (0.74) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL25120998 | 1.00 | DGKA (0.74) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL25121055 | 1.00 | DGKA (0.74) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL25181489 | 1.00 | DGKA (0.74) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL23605993 | 1.00 | DGKA (0.74) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL25259134 | 1.00 | DGKA (0.74) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL25342186 | 1.00 | DGKA (0.74) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL24588753 | 1.00 | DGKA (0.74) | DGKANAAAPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113039174-B | Ionizable amine lipids | 英特利亚治疗股份有限公司 | 2023-11-17 | — | — | CN | disclosed |
| US-20220009878-A1 | IONIZABLE AMINE LIPIDS | INTELLIA THERAPEUTICS, INC. | 2022-01-13 | — | — | US | disclosed |
| US-20220009878-A1 | IONIZABLE AMINE LIPIDS | INTELLIA THERAPEUTICS, INC. | 2022-01-13 | — | — | US | disclosed |
| EP-3860972-A1 | IONIZABLE AMINE LIPIDS | Intellia Therapeutics, Inc. (US) | 2021-08-11 | — | — | EP | disclosed |
| CN-113039174-A | Ionizable amine lipids | 英特利亚治疗股份有限公司 | 2021-06-25 | — | — | CN | disclosed |
| WO-2020072605-A1 | IONIZABLE AMINE LIPIDS | INTELLIA THERAPEUTICS, INC. (US) | 2020-04-09 | — | — | WO | disclosed |
| WO-2020072605-A1 | IONIZABLE AMINE LIPIDS | INTELLIA THERAPEUTICS, INC. (US) | 2020-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220009878-A1 | IONIZABLE AMINE LIPIDS | PHOSPHO1, SGMS1, SGMS2 | DGKA 312/4885NAAA 36/4885PRSS1 3614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.