Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25353226 | 0.83 | CYP2D6 (0.39) | POLBSMN1; SMN2KDM4CCYP2C19ALDH1A1 | |
| SCHEMBL8962237 | 0.75 | POLB (0.38) | POLBDPP4HDAC6PREPFAP | |
| SCHEMBL26629354 | 0.75 | PREP (0.40) | POLBDPP4HDAC6PREPFAP | |
| SCHEMBL24574899 | 0.75 | SMN1; SMN2 (0.45) | POLBDPP4HDAC6PREPFAP | |
| SCHEMBL22991094 | 0.74 | POLB (0.39) | POLBDPP4HDAC6PREPFAP | |
| Ammonia Solution, Strong SCHEMBL27973098 | 0.73 | POLB (0.37) | POLBDPP4HDAC6PREPFAP | |
| SCHEMBL4478224 | 0.73 | POLB (0.31) | POLBKDM4CALDH1A1 | |
| SCHEMBL12920690 | 0.73 | CNR2 (0.38) | POLBDPP4HDAC6PREPFAP | |
| SCHEMBL12175396 | 0.72 | POLB (0.42) | POLBL3MBTL1KDM4CKDM4ECYP2C19 | |
| SCHEMBL28001419 | 0.71 | DPP4 (0.32) | POLBDPP4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970107-B1 | PHOTOSWITCHABLE HDAC INHIBITORS | MASSACHUSETTS GEN HOSPITAL (US) | 2023-11-15 | — | — | EP | claimed |
| EP-3538510-B1 | PROCESS FOR THE PREPARATION OF MONO-PROTECTED ALPHA,OMEGA-DIAMINO ALKANES | BYONDIS BV (NL) | 2021-01-06 | — | — | EP | claimed |
| US-10815194-B2 | Process for the preparation of mono-protected α,ω-diamino alkanes | BYONDIS B.V. (NL) | 2020-10-27 | — | — | US | claimed |
| EP-3538510-A1 | PROCESS FOR THE PREPARATION OF MONO-PROTECTED alpha,omega-DIAMINO ALKANES | Synthon Biopharmaceuticals B.V. (NL) | 2019-09-18 | — | — | EP | claimed |
| WO-2018086993-A1 | PROCESS FOR THE PREPARATION OF MONO-PROTECTED alpha,omega-DIAMINO ALKANES | SYNTHON BIOPHARMACEUTICALS B.V. (NL) | 2018-05-17 | — | — | WO | claimed |
| US-20130304089-A1 | PERYLENEQUINONE DERIVATIVES AND USES THEREOF | QUEST PHARMATECH INC. (CA) | 2013-11-14 | — | — | US | claimed |
| US-20240125773-A1 | COMPOSITIONS AND METHODS FOR PREVENTING NON-SPECIFIC INTERACTIONS BETWEEN POLYMER DYES-ANTIBODY CONJUGATES | BECKMAN COULTER, INC. | 2024-04-18 | — | — | US | disclosed |
| EP-4334395-A1 | UV-ABSORBING POLYMERS, COMPOSITIONS AND USES THEREOF | Beckman Coulter, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |
| US-20240075151-A1 | CONJUGATES OF TUMOR NECROSIS FACTOR INHIBITORS TO FUNCTIONALIZED POLYMERS | FISH & RICHARDSON PC | 2024-03-07 | — | — | US | disclosed |
| WO-2024044327-A1 | DHNT MONOMERS AND POLYMER DYES WITH MODIFIED PHOTOPHYSICAL PROPERTIES | BECKMAN COULTER, INC. (US) | 2024-02-29 | — | — | WO | disclosed |
| US-20240052092-A1 | PHOTOACTIVE MACROMOLECULES AND USES THEREOF | BECKMAN COULTER, INC. | 2024-02-15 | — | — | US | disclosed |
| US-20240011976-A1 | ADDITIVES FOR REDUCING NON-SPECIFIC INTERACTIONS BETWEEN FLUORESCENT POLYMER CONJUGATES AND CELLS IN A BIOLOGICAL SAMPLE | BECKMAN COULTER, INC. | 2024-01-11 | — | — | US | disclosed |
| WO-2024007016-A2 | NOVEL FLUORESCENT DYES AND POLYMERS FROM DIHYDROPHENANTHRENE DERIVATIVES | BECKMAN COULTER, INC. (US) | 2024-01-04 | — | — | WO | disclosed |
| EP-2638009-A2 | FLUORINATED HDAC INHIBITORS AND USES THEREOF | President and Fellows of Harvard College (US) | 2013-09-18 | — | — | EP | disclosed |
| WO-2013070943-A2 | SMALL MOLECULE SCREEN FOR INHIBITORS OF NFAT:AP-1:DNA INTERACTIONS | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2013-05-16 | — | — | WO | disclosed |
| US-20130040998-A1 | FLUORINATED HDAC INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2013-02-14 | — | — | US | disclosed |
| WO-2012112922-A1 | METHODS FOR SYNTHESIZING MOLYBDOPTERIN PRECURSOR Z DERIVATIVES | ALEXION PHARMACEUTICALS, INC. (US) | 2012-08-23 | — | — | WO | disclosed |
| US-20120208889-A1 | CLASS- AND ISOFORM-SPECIFIC HDAC INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUE, INC. (US) | 2012-08-16 | — | — | US | disclosed |
| US-20120178940-A1 | Functionalized Polymers | QUIAPEG AB (SE) | 2012-07-12 | — | — | US | disclosed |
| WO-2011084991-A2 | FLUORINATED HDAC INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130304089-A1 | PERYLENEQUINONE DERIVATIVES AND USES THEREOF | CYP27B1, CYP27A1, PCNA | POLB 591/4885DPP4 4078/4885HDAC6 4066/4885 |
| US-20120178940-A1 | Functionalized Polymers | PARG, PUF60, PCBP1 | POLB 669/4885DPP4 4592/4885HDAC6 636/4885 |
| US-10815194-B2 | Process for the preparation of mono-protected α,ω-diamino alkanes | FCGRT, CD22, DEGS1 | POLB 347/4885DPP4 850/4885HDAC6 2417/4885 |
| US-20240075151-A1 | CONJUGATES OF TUMOR NECROSIS FACTOR INHIBITORS TO FUNCTIONALIZED POLYMERS | TNF, TNFRSF1A, TNFSF11 | POLB 2216/4885DPP4 4064/4885HDAC6 624/4885 |
| US-20130040998-A1 | FLUORINATED HDAC INHIBITORS AND USES THEREOF | HDAC1, HDAC5, HDAC6 | POLB 1226/4885DPP4 2274/4885HDAC6 3/4885 |
| US-20120208889-A1 | CLASS- AND ISOFORM-SPECIFIC HDAC INHIBITORS AND USES THEREOF | HDAC1, HDAC5, HDAC6 | POLB 3822/4885DPP4 2528/4885HDAC6 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.