Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1819157 | 0.91 | TSHR (0.36) | THRBTSHRALDH1A1 | |
| SCHEMBL10941241 | 0.79 | HCAR2 (0.33) | TSHR | |
| SCHEMBL432550 | 0.74 | TSHR (0.38) | THRBTSHRALDH1A1 | |
| SCHEMBL1219576 | 0.73 | TSHR (0.40) | THRBTSHRALDH1A1 | |
| SCHEMBL1155535 | 0.73 | TSHR (0.33) | TSHR | |
| SCHEMBL14269217 | 0.72 | TSHR (0.37) | THRBTSHRALDH1A1 | |
| SCHEMBL6685867 | 0.72 | THRB (0.38) | THRBTSHRALDH1A1 | |
| SCHEMBL26658670 | 0.71 | TSHR (0.47) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL239023 | 0.71 | THRB (0.74) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL9421556 | 0.71 | THRB (0.74) | THRBTSHRALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120115979-A1 | CHLORINATED POLYMER ENHANCING WETTABILITY OF SILICONE HYDROGEL, SILICONE HYDROGEL COMPRISING THE SAME AND OCULAR ARTICLE MADE THEREFROM | FAR EASTERN NEW CENTURY CORPORATION (TW) | 2012-05-10 | — | — | US | claimed |
| US-20110166248-A1 | COPOLYMER FOR ENHANCING THE wETTABILITY OF SILICONE HYDROGEL, SILICONE HYDROGEL COMPOSITION COMPRISING THE SAME AND OCULAR ARTICLE MADE THEREFROM | FAR EASTERN NEW CENTURY CORPORATION | 2011-07-07 | — | — | US | claimed |
| US-8492513-B2 | Method for enhancing water content of silicone hydrogel contact lens | FAR EASTERN NEW CENTURY CORPORATION (TW) | 2013-07-23 | — | — | US | disclosed |
| US-20120214899-A1 | METHOD FOR ENHANCING WATER CONTENT OF SILICONE HYDROGEL CONTACT LENS | FAR EASTERN NEW CENTURY CORPORATION (TW) | 2012-08-23 | — | — | US | disclosed |
| US-20120115979-A1 | CHLORINATED POLYMER ENHANCING WETTABILITY OF SILICONE HYDROGEL, SILICONE HYDROGEL COMPRISING THE SAME AND OCULAR ARTICLE MADE THEREFROM | FAR EASTERN NEW CENTURY CORPORATION (TW) | 2012-05-10 | — | — | US | disclosed |
| US-20110166248-A1 | COPOLYMER FOR ENHANCING THE wETTABILITY OF SILICONE HYDROGEL, SILICONE HYDROGEL COMPOSITION COMPRISING THE SAME AND OCULAR ARTICLE MADE THEREFROM | FAR EASTERN NEW CENTURY CORPORATION | 2011-07-07 | — | — | US | disclosed |