Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 5/20 | 0.53 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417306 | 0.91 | TRHR (0.64) | TRHR | |
| SCHEMBL2197324 | 0.90 | TRHR (0.56) | TRHR | |
| SCHEMBL5804619 | 0.88 | TRHR (0.54) | TRHR | |
| SCHEMBL11328954 | 0.86 | TRHR (0.54) | TRHR | |
| SCHEMBL30958102 | 0.85 | TRHR (0.53) | TRHR | |
| SCHEMBL11327973 | 0.85 | TRHR (0.66) | TRHR | |
| SCHEMBL31230968 | 0.82 | DPP7 (0.53) | TGM2 | |
| SCHEMBL11733472 | 0.80 | HDAC3 (0.47) | — | |
| SCHEMBL31199130 | 0.80 | MEN1 (0.48) | TRHR | |
| SCHEMBL1373186 | 0.80 | TRHR (0.65) | TRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166063-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NEKTAR THERAPEUTICS (US) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166063-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NGLY1, CD44, IAPP | TRHR 2370/4885TGM2 1681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.