Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 10/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 10/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11740264 | 0.88 | HDAC3 (0.46) | HDAC3HDAC11HDAC6HDAC1HDAC2 | |
| SCHEMBL29776748 | 0.86 | HDAC3 (0.48) | HDAC3HDAC11HDAC6HDAC1HDAC2 | |
| SCHEMBL23300537 | 0.86 | HDAC3 (0.48) | HDAC3HDAC11HDAC6HDAC1HDAC2 | |
| SCHEMBL23300538 | 0.86 | HDAC3 (0.48) | HDAC3HDAC11HDAC6HDAC1HDAC2 | |
| SCHEMBL11173161 | 0.84 | FOLH1 (0.46) | HDAC3HDAC11HDAC6HDAC1HDAC2 | |
| SCHEMBL22319322 | 0.84 | FOLH1 (0.46) | HDAC3HDAC11HDAC6HDAC1HDAC2 | |
| SCHEMBL22319323 | 0.84 | FOLH1 (0.46) | HDAC3HDAC11HDAC6HDAC1HDAC2 | |
| SCHEMBL10661794 | 0.82 | HDAC3 (0.43) | HDAC3HDAC11HDAC6HDAC1HDAC2 | |
| SCHEMBL159688 | 0.82 | OPRK1 (0.44) | HDAC3HDAC11HDAC6HDAC1HDAC2 | |
| SCHEMBL159687 | 0.82 | OPRK1 (0.44) | HDAC3HDAC11HDAC6HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053588-A | PYROGLUTAMIC ACID AMIDES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-10-11 | — | — | US | disclosed |