SCHEMBL21834282

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21834262	0.90	MAOB (0.39)	CYP2C9GRIN2BGRIN1
	SCHEMBL21834274	0.87	FFAR1 (0.36)	GRIN2BGRIN1GPR88
	SCHEMBL21834241	0.84	KDM4E (0.36)	LMNAGRIN2BGRIN1ALDH1A1KDM4E
	SCHEMBL23243855	0.83	NR3C2 (0.33)	LMNAKMT2AGRIN2BGRIN1
	SCHEMBL21834271	0.83	GRIN2B (0.38)	GRIN2BGRIN1
	SCHEMBL21834280	0.83	CYP17A1 (0.39)	CYP2C9GRIN2BGRIN1ALDH1A1GPR88
	SCHEMBL23243869	0.82	GPR88 (0.41)	CYP2C9CYP1A2MEN1LMNAKMT2A
	SCHEMBL23243860	0.81	NR3C2 (0.32)	KMT2AGRIN2BGRIN1
	SCHEMBL23243854	0.80	NR3C2 (0.32)	LMNAKMT2A
	SCHEMBL23243841	0.80	MAOB (0.38)	CYP2C9GRIN2BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.