⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697284 | 0.71 | — | — | |
| SCHEMBL8345883 | 0.65 | ALDH1A1 (0.30) | — | |
| SCHEMBL21725827 | 0.61 | — | — | |
| SCHEMBL20711402 | 0.61 | LMNA (0.34) | — | |
| SCHEMBL1259877 | 0.61 | — | — | |
| SCHEMBL23322796 | 0.56 | — | — | |
| SCHEMBL22432541 | 0.56 | — | — | |
| SCHEMBL14184756 | 0.55 | — | — | |
| SCHEMBL2148865 | 0.54 | ALDH1A1 (0.47) | — | |
| SCHEMBL20781 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109232474-B | 1,2, 4-thiadiazole compound and preparation method and application thereof | 武汉尚赛光电科技有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-109438435-B | 1,2, 4-thiadiazole compound and preparation method and application thereof | 武汉尚赛光电科技有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-109369567-B | 1,2, 4-thiadiazole compound and preparation method and application thereof | 武汉尚赛光电科技有限公司 | 2021-03-02 | — | — | CN | disclosed |
| WO-2020062375-A1 | 1,2,4-THIADIAZOLE COMPOUNDS AND PREPARATION METHOD THEREFOR AND USE THEREOF | 武汉尚赛光电科技有限公司 | 2020-04-02 | — | — | WO | disclosed |
| WO-2020062375-A1 | 1,2,4-THIADIAZOLE COMPOUNDS AND PREPARATION METHOD THEREFOR AND USE THEREOF | 武汉尚赛光电科技有限公司 | 2020-04-02 | — | — | WO | disclosed |