Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 2/20 | 0.37 |
| ▸ | BPGM | P07738 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21834617 | 0.82 | HDAC3 (0.45) | HDAC3HDAC1HDAC6KDM4ELMNA | |
| SCHEMBL21834625 | 0.81 | HDAC3 (0.42) | HDAC3HDAC1HDAC6KDM4ELMNA | |
| SCHEMBL21834677 | 0.80 | HDAC3 (0.42) | HDAC3HDAC1HDAC6L3MBTL1DYRK1A | |
| SCHEMBL21812752 | 0.80 | HDAC3 (0.48) | HDAC3HDAC1HDAC6KDM4ELMNA | |
| SCHEMBL21834557 | 0.79 | HDAC3 (0.41) | HDAC3HDAC1HDAC6KDM4ELMNA | |
| SCHEMBL21812556 | 0.78 | HDAC3 (0.48) | HDAC3HDAC1HDAC6KDM4ELMNA | |
| SCHEMBL21812974 | 0.78 | HDAC1 (0.48) | HDAC3HDAC1HDAC6KDM4EKDM4A | |
| SCHEMBL19114635 | 0.78 | HDAC3 (0.60) | HDAC3HDAC1HDAC6PI4KBKDM4A | |
| SCHEMBL16020352 | 0.78 | HDAC3 (0.48) | HDAC3HDAC1HDAC6KDM4ELMNA | |
| SCHEMBL21812678 | 0.76 | MAPK1 (0.53) | HDAC3HDAC1HDAC6LMNAKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020064175-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | ANTABIO SAS (FR) | 2020-04-02 | — | — | WO | disclosed |