Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16020352 | 0.88 | HDAC3 (0.48) | HDAC3HDAC1HDAC6NPC1RAB9A | |
| SCHEMBL20691496 | 0.86 | HDAC3 (0.66) | HDAC3HDAC1HDAC6SREBF2 | |
| SCHEMBL21812678 | 0.79 | MAPK1 (0.53) | HDAC3HDAC1HDAC6NPC1RAB9A | |
| SCHEMBL31147895 | 0.78 | HDAC3 (0.49) | HDAC3HDAC1HDAC6KDM4A | |
| SCHEMBL21812750 | 0.78 | HDAC3 (0.50) | HDAC3HDAC1HDAC6NPC1RAB9A | |
| SCHEMBL21834564 | 0.78 | HDAC3 (0.48) | HDAC3HDAC1HDAC6PI4KBKDM4A | |
| SCHEMBL21812752 | 0.78 | HDAC3 (0.48) | HDAC3HDAC1HDAC6PI4KBKDM4A | |
| SCHEMBL215719 | 0.78 | HDAC3 (0.51) | HDAC3HDAC1HDAC6KDM4A | |
| SCHEMBL21812652 | 0.77 | LMNA (0.53) | HDAC3HDAC1HDAC6NPC1RAB9A | |
| SCHEMBL21812758 | 0.77 | HDAC3 (0.49) | HDAC3HDAC1HDAC6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2708534-B1 | THIAZOLE COMPOUND AND PREPARATION METHOD AND USE THEREOF | SHANGHAI THEORION PHARMACEUTICAL CO LTD (CN) | 2017-07-12 | — | — | EP | disclosed |