Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM5A | P29375 | 1/20 | 0.46 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2833079 | 0.77 | SMN1; SMN2 (0.52) | KMT2AKDM4ELMNAALDH1A1ADORA2A | |
| SCHEMBL30902246 | 0.77 | SMN1; SMN2 (0.52) | KMT2AKDM4ELMNAALDH1A1ADORA2A | |
| SCHEMBL13475580 | 0.77 | CNR2 (0.55) | KMT2AKDM4ECES2CES1LMNA | |
| SCHEMBL10964846 | 0.77 | KMT2A (0.51) | KMT2AKDM4ECES2CES1LMNA | |
| SCHEMBL31369148 | 0.75 | KMT2A (0.75) | KMT2AKDM4ECES2CES1LMNA | |
| SCHEMBL87791 | 0.75 | KMT2A (0.75) | KMT2AKDM4ECES2CES1LMNA | |
| SCHEMBL17099640 | 0.75 | PI4KA (0.52) | KMT2AKDM4ELMNAALDH1A1ADORA2A | |
| Lithium Ion SCHEMBL21818896 | 0.75 | PI4KA (0.47) | KMT2AKDM4ELMNAALDH1A1ADORA2A | |
| SCHEMBL31385237 | 0.75 | PI4KA (0.52) | KMT2AKDM4ELMNAALDH1A1ADORA2A | |
| Charcoal, Activated SCHEMBL8358164 | 0.73 | KMT2A (0.72) | KMT2AKDM4ECES2CES1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3856178-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | Janssen Pharmaceutica NV (BE) | 2021-08-04 | — | — | EP | disclosed |
| WO-2020065613-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |