SCHEMBL2183501

SCHEMBL2183501

CCN(C(=O)CN)[C@H]([C]=O)CCCCN

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 6/20 0.36
GSR P00390 1/20 0.34
RNPEP Q9H4A4 1/20 0.33
GNAI3 P08754 1/20 0.32
GNAO1 P09471 1/20 0.32
GNAI1 P63096 1/20 0.32
DPP8 Q6V1X1 1/20 0.30
DPP9 Q86TI2 1/20 0.30
DPP7 Q9UHL4 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7742963 0.81
SCHEMBL7360733 0.77 GABRR1 (0.31)
SCHEMBL5150388 0.76 CPB2 (0.39) CPB2GSRRNPEP
SCHEMBL3952652 0.73 GSR (0.38) CPB2GSRRNPEPGNAI3GNAO1
SCHEMBL7748340 0.72 GAA (0.30)
SCHEMBL15529854 0.71 CHRM2 (0.34) CPB2GSRRNPEP
SCHEMBL6228775 0.71 FFAR4 (0.41) CPB2GNAI3GNAO1GNAI1
SCHEMBL22558026 0.70 FFAR4 (0.41) CPB2GNAI3GNAO1GNAI1
SCHEMBL5133687 0.69 GSR (0.35) CPB2GSRRNPEP
SCHEMBL5133688 0.69 GSR (0.35) CPB2GSRRNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110166063-A1 POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES NEKTAR THERAPEUTICS (US) 2011-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110166063-A1 POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES NGLY1, CD44, IAPP CPB2 284/4885GSR 4555/4885RNPEP 173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.