Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 2/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23175320 | 0.91 | CXCR2 (0.40) | CXCR2GRIK1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL28039165 | 0.81 | CXCR2 (0.37) | CXCR2GRIK1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL28664691 | 0.80 | CXCR2 (0.39) | CXCR2GRIK1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL21835138 | 0.76 | CXCR2 (0.41) | CXCR2GRIK1MEN1KMT2AMAPT | |
| SCHEMBL31218238 | 0.74 | RAB9A (0.39) | CXCR2GRIK1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL4538114 | 0.74 | IDO1 (0.40) | CXCR2GRIK1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL20694514 | 0.74 | ALDH1A1 (0.48) | CXCR2RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL30462809 | 0.74 | CA1 (0.41) | CXCR2RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL12425149 | 0.74 | CA1 (0.41) | CXCR2RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL18250335 | 0.73 | CXCR2 (0.58) | CXCR2GRIK1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020067595-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME | 희성소재(주) | 2020-04-02 | — | — | WO | disclosed |